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Kim, Taesung
Microfluidics & Nanomechatronics Lab (μFNM)
Research Interests
  • Micro-/Nanofluidics
  • BioMEMS
  • Nanomechatronics

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Active alignment of microtubules with electric fields

Cited 39 times inthomson ciCited 43 times inthomson ci
Title
Active alignment of microtubules with electric fields
Author
Kim, TaesungKao, Ming-TseHasselbrink, Ernest F.Meyhoefer, Edgar
Keywords
Active alignment; Microtubule translocation; Microtubules; Surface density
Issue Date
2007-01
Publisher
AMER CHEMICAL SOC
Citation
NANO LETTERS, v.7, no.1, pp.211 - 217
Abstract
The direction of translocation of microtubules on a surface coated with kinesin is usually random. Here we demonstrate and quantify the rate at which externally applied electric fields can direct moving microtubules parallel to the field by deflecting their leading end toward the anode. Effects of electric field strength, kinesin surface density, and microtubule translocation speed on the rate of redirection of microtubules were analyzed statistically. Furthermore, we demonstrated that microtubules can be steered in any desired direction via manipulation of externally applied E-fields.
URI
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DOI
10.1021/nl061474k
ISSN
1530-6984
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