BROWSE

Related Researcher

Author's Photo

Cho, Hyungjoon
Biomedical Imaging Science and Engineering Lab(BISE)
Research Interests
  • Imaging tumor microenvironments, susceptibility contrast based MR structural imaging, ultra fast acquisitions of dynamic MR, algorithm/Hardware development for magnetic particle imaging

ITEM VIEW & DOWNLOAD

Dual MRI T1 and T2 (*) contrast with size-controlled iron oxide nanoparticles

Cited 0 times inthomson ciCited 0 times inthomson ci
Title
Dual MRI T1 and T2 (*) contrast with size-controlled iron oxide nanoparticles
Author
Jung, HoesuPark, BumwooLee, ChangkyungCho, JunghunSuh, JiyeonPark, JangyeonKim, YoungroKim, JeongkonCho, GyunggooCho, Hyungjoon
Issue Date
2014-11
Publisher
ELSEVIER SCIENCE BV
Citation
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, v.10, no.8, pp.1679 - 1689
Abstract
Contrast-enhancing magnetic resonance mechanism, employing either positive or negative signal changes, has contrast-specific signal characteristics. Although highly sensitive, negative contrast typically decreases the resolution and spatial specificity of MRI, whereas positive contrast lacks a high contrast-to-noise ratio but offers high spatial accuracy. To overcome these individual limitations, dual-contrast acquisitions were performed using iron oxide nanoparticles and a pair of MRI acquisitions. Specifically, vascular signals in MR angiography were positively enhanced using ultrashort echo (UTE) acquisition, which provided highly resolved vessel structures with increased vessel/tissue contrast. In addition, fast low angle shot (FLASH) acquisition yielded strong negative vessel contrast, resulting in the higher number of discernible vessel branches than those obtained from the UTE method. Taken together, the high sensitivity of the negative contrast delineated ambiguous vessel regions, whereas the positive contrast effectively eliminated the false negative contrast areas (e.g., airways and bones), demonstrating the benefits of the dual-contrast method.
URI
https://scholarworks.unist.ac.kr/handle/201301/5106
URL
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84908565636
DOI
10.1016/j.nano.2014.05.003
ISSN
1549-9634
Appears in Collections:
BME_Journal Papers
Files in This Item:
There are no files associated with this item.

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU