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Kim, Miran
Research Interests
  • My research mainly focuses on secure computation, which aims to develop advanced cryptographic primitives to protect the sensitive data of individuals. I have been actively working on the development of privacy-preserving protocols in a wide range of applications such as cyber-physical systems, data query processing, genomic computation, and machine learning.

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A secure system for genomics clinical decision support

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Title
A secure system for genomics clinical decision support
Author
Karimi, SeemeenJiang, XiaoqianDolin, Robert H.Kim, MiranBoxwala, Aziz
Issue Date
2020-12
Publisher
Academic Press
Citation
JOURNAL OF BIOMEDICAL INFORMATICS, v.112, pp.103602
Abstract
We developed a prototype genomic archiving and communications system to securely store genome data and provide clinical decision support (CDS). This system operates on a client-server model. The client encrypts the data, and the server stores data and performs the computations necessary for CDS. Computations are directly performed on encrypted data, and the client decrypts results. The server cannot decrypt inputs or outputs, which provides strong guarantees of security. We have validated our system with three genomics-based CDS applications. The results demonstrate that it is possible to resolve a long-standing dilemma in genomic data privacy and accessibility, by using a principled cryptographical framework and a mathematical representation of genome data and CDS questions.
URI
https://scholarworks.unist.ac.kr/handle/201301/48762
URL
https://www.sciencedirect.com/science/article/pii/S1532046420302306?dgcid=rss_sd_all
DOI
10.1016/j.jbi.2020.103602
ISSN
1532-0464
Appears in Collections:
CSE_Journal Papers
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