Source separation and recovery of human urine have often been proposed as an effective way to achieve a more sustainable waste-to-resource cycle. Its high density of available macronutrients (N-P-K) in urine makes it an ideal raw material for the production of fertiliser. However, to improve the safety and public acceptance of urine-based fertilisers, odour and pathogens must be removed. In this work, low-temperature DCMD was investigated a mean to produce a non-odorous high-concentration liquid fertiliser. The effectiveness of urine-fertiliser in hydroponically growing leafy vegetables was benchmarked with a commercial solution. Also, prior to the DCMD, urine was biologically oxidised through an MBR which removed over 95% of the DOC and converted almost 50% of the NH3 into NO3-. The results showed that, despite the high salinity and high LMW organics in human urine, MD was still able to achieve a final product with TDS concentration up to 280 g.L-1. A sharp flux decline was measured after 80% water recovery, but alkaline cleaning effectively removed the thick fouling layer and fully recovered the initial flux. When used to grow lettuce and Pak Choi hydroponically, the produced urine fertiliser achieved promising performances as the biomass from the aerial part of the plants was often similar to the one obtained with commercial fertilisers. Overall, this article investigates the whole urine-to-biomass cycle, from collection to treatment to plant growth tests. (C) 2020 Elsevier Ltd. All rights reserved.