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- Cho, Hyungjoon
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Susceptibility-related phase contrast associated with the alterations of myelo- architecture in adult-onset leukoencephalopathy with neuroaxonal spheroids and pigmented glia
- Author(s)
- Lee, Hansol, Kim, Minkyeong, Cho, Hyungjoon, Chun, Se Young, Huh, Gi Yeong, Kim, Eun-Joo, Lee, Jae-Hyeok
- Issued Date
- 2017-04-25
- Citation
- ISMRM 25TH ANNUAL MEETING & EXHIBITION
- Abstract
- To investigate the origin of susceptibility-weighted imaging (SWI) contrast in frontal white matters of adult-onset leukoencephalopathy with neuroaxonal spheroids and pigmented glia (ALSP), we performed a combined post-mortem magnetic resonance imaging (MRI) and histological study of ALSP pathology. The myelin architectural changes, marked central myelin loss with preserved U-fibers beneath cortical gray matter, mainly contributed to the susceptibility contrast.
- Publisher
- International Society for Magnetic Resonance in Medicine
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