There are no files associated with this item.
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 1198 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1194 | - |
dc.citation.title | ACS MACRO LETTERS | - |
dc.citation.volume | 1 | - |
dc.contributor.author | Kim, Hyunkyu | - |
dc.contributor.author | Kong, Young Ji | - |
dc.contributor.author | Jeong, Eun Sun | - |
dc.contributor.author | Kang, Sebyung | - |
dc.contributor.author | Kim, Kyoung Taek | - |
dc.date.accessioned | 2023-12-22T04:40:10Z | - |
dc.date.available | 2023-12-22T04:40:10Z | - |
dc.date.created | 2013-07-09 | - |
dc.date.issued | 2012-10 | - |
dc.description.abstract | Polymers containing organoboronic acids have recently gained interest as sugar-responsive materials owing to the reversible binding of saccharides to boronic acids, which triggers a change in the physical and chemical properties of these polymers, such as their water solubility. In particular, the ability of these polymers to bind glucose has attracted considerable attention because of the promise of these materials for the development of sensors and drug delivery systems for glucose-related human diseases, such as diabetes. We report here a new class of sugar-responsive polymers that are based on a sequence-specific copolymer of styreneboroxole and N-functionalized maleimide. The reversible addition-fragmentation and chain transfer (RAFT) polymerization of this pair of monomers ensured that a glucose receptor alternates with a nonresponsive solubilizing group throughout the sugar-responsive polymer chain. Due to the presence of hydrophilic solubilizing groups beween the solubility-switching boroxole moieties in the membrane-forming block, the polymersomes of the block copolymers responded to a lower level of glucose in the medium, resulting in diassembly of the bilayer membrane under a physiologically relevant pH and glucose level. | - |
dc.identifier.bibliographicCitation | ACS MACRO LETTERS, v.1, no.10, pp.1194 - 1198 | - |
dc.identifier.doi | 10.1021/mz3004192 | - |
dc.identifier.issn | 2161-1653 | - |
dc.identifier.scopusid | 2-s2.0-84886235399 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/3573 | - |
dc.identifier.url | http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=20&SID=Y2PVknxoxMhoJXBWHvD&page=1&doc=1 | - |
dc.identifier.wosid | 000309804800010 | - |
dc.language | 영어 | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Glucose-Responsive Disassembly of Polymersomes of Sequence-Specific Boroxole-Containing Block Copolymers under Physiologically Relevant Conditions | - |
dc.type | Article | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | BORONIC ACIDS | - |
dc.subject.keywordPlus | INSULIN | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | CHAINS | - |
dc.subject.keywordPlus | WATER | - |
dc.subject.keywordPlus | PH | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Tel : 052-217-1404 / Email : scholarworks@unist.ac.kr
Copyright (c) 2023 by UNIST LIBRARY. All rights reserved.
ScholarWorks@UNIST was established as an OAK Project for the National Library of Korea.