19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015, pp.446 - 448
Abstract
Research on specific drug response of circulating tumor cells provides very important information for treatment of cancer patients at a patient-specific level. Consequently, platform for high capture efficiency of CTCs are essential for clinical evaluation of patient-specific drug response of CTCs. In this study, the BT20 cells with an ultra-low abundance range were captured by STR-SiNW platform with high capture efficiency. Specific drug responses of target cells captured on STR-SiNW platforms were analyzed using tamoxifen or docetaxel. In addition, CTCs were successfully captured and evaluated their size distribution from the blood of breast cancer patient.
Publisher
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015