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- Kim, Taesung
- Microfluidics & Nanomechatronics Lab.
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A SILICON NANOWIRE PLATFORM FOR DRUG RESPNOSE OF CAPTURED BT20 CELLS AND EVALUATION OF CIRCULATING TUMOR CELLS FROM BREAST CANCER PATIENT’S BLOOD
- Author(s)
- Kim, Dong-Joo, Kim, Taesung, Lee, Sang-Kwon
- Issued Date
- 2015-10-26
- Citation
- 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015, pp.446 - 448
- Abstract
- Research on specific drug response of circulating tumor cells provides very important information for treatment of cancer patients at a patient-specific level. Consequently, platform for high capture efficiency of CTCs are essential for clinical evaluation of patient-specific drug response of CTCs. In this study, the BT20 cells with an ultra-low abundance range were captured by STR-SiNW platform with high capture efficiency. Specific drug responses of target cells captured on STR-SiNW platforms were analyzed using tamoxifen or docetaxel. In addition, CTCs were successfully captured and evaluated their size distribution from the blood of breast cancer patient.
- Publisher
- 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
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