the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015)
Abstract
We report a novel electrochemical glucose sensor employing carbon interdigitated array (IDA) nanoelectrodes for electrochemical-enzymatic redox cycling of the redox species ([Fe(CN)6]3/[Fe(CN)6]4-) between the glucose oxidase (GOx) and two combs of IDA nanoelectrodes. The IDA nanoelectrodes were fabricated using a simple, cost-effective, reproducible microfabrication technology known as carbon-microelectromechanical-systems (C-MEMS). The surface modification scheme involves the selective electrochemical reduction of aryl diazonium salts, followed by the immobilization of GOx. The current response evaluation of both the combs of IDA nanoelectrodes, attributes that sensitivity of glucose detection increased ∼ 2.5 times using unmodified surface of comb 2 along with comb 1.