File Download
There are no files associated with this item.
SFX Link
- Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
- Bielawski, Christopher W.
Views & Downloads
Detailed Information
Cited time in 
Cited time in 
Cited time in
Metadata Downloads
A Mechanochemical Approach to Deracemization
- Author(s)
- Wiggins, Kelly M., Bielawski, Christopher W.
- Issued Date
- 2012
- Citation
- ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.51, no.7, pp.1640 - 1643
- Abstract
- Good combination : Enantioselective enzymatic hydrolysis was combined with a mechanically facilitated racemization process to prepare (S )‐1,1′‐binapthol ((S )‐ binol) in high yield and enantiopurity from a racemic precursor in a single step (see scheme). The enzyme cholesterol esterase stereoselectively hydrolyzes esters of (S )‐ binol and ultrasound was applied to achieve mechanically facilitated racemization of the precursor material.
- Publisher
- WILEY-V C H VERLAG GMBH
- ISSN
- 1433-7851
- Keyword (Author)
- atropisomerism, chiral resolution, mechanochemistry, polymers, ultrasound
- Keyword
- ASYMMETRIC TRANSFORMATIONS, ENZYMES, RESOLUTIONS, CATALYSIS, POLYMERS
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.