File Download
There are no files associated with this item.
SFX Link
- Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
- Grzybowski, Bartosz A.
Views & Downloads
Detailed Information
Cited time in 
Cited time in 
Cited time in
Metadata Downloads
Rewiring Chemistry: Algorithmic Discovery and Experimental Validation of One-Pot Reactions in the Network of Organic Chemistry
- Author(s)
- Gothard, Chris M., Soh, Siowling, Gothard, Nosheen A., Kowalczyk, Bartlomiej, Wei, Yanhu, Baytekin, Bilge, Grzybowski, Bartosz A.
- Issued Date
- 2012
- Citation
- ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.51, no.32, pp.7922 - 7927
- Abstract
- Computational algorithms are used to identify sequences of reactions that can be performed in one pot. These predictions are based on over 86 000 chemical criteria by which the putative sequences are evaluated. The “raw” algorithmic output is then validated experimentally by performing multiple two‐, three‐, and even four‐step sequences. These sequences “rewire” synthetic pathways around popular and/or important small molecules.
- Publisher
- WILEY-V C H VERLAG GMBH
- ISSN
- 1433-7851
- Keyword (Author)
- algorithms, chemical networks, one-pot reactions, synthetic methods
- Keyword
- CHEMICAL PROBLEMS, ECONOMY
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.