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GrzybowskiBartosz Andrzej

Grzybowski, Bartosz A.
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Tomography and Static-Mechanical Properties of Adherent Cells

Author(s)
Soh, SiowlingKandere-Grzybowska, KristianaMahmud, GoherHuda, SabilPatashinski, Alexander Z.Grzybowski, Bartosz A.
Issued Date
2012-11
DOI
10.1002/adma.201200492
URI
https://scholarworks.unist.ac.kr/handle/201301/33116
Fulltext
https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201200492
Citation
ADVANCED MATERIALS, v.24, no.42, pp.5719 - 5726
Abstract
A tomography approach is used to reconstruct 3D cell shapes and, simultaneously, the shapes/positions of the nuclei within these cells. Subjecting the cells to well-defined microconfinements of various diameters allow for relating the steady-state shapes of cells to their static-mechanical properties. The observed shapes show striking regularities between different cell types and all fit to a model that takes into account the cell membrane, cortical actin, and the nucleus.
Publisher
WILEY-V C H VERLAG GMBH
ISSN
0935-9648
Keyword (Author)
cell mechanicscell shapesconfocal microscopymicropatterningcortical actin
Keyword
RED-BLOOD-CELLLIVING CELLSSHAPE TRANSFORMATIONSSPONTANEOUS-CURVATUREMEMBRANE CURVATUREACTIN NETWORKSCYTOSKELETONELASTICITYVESICLESMODEL

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