Objective The aim of this study is to examine the interactive effects of display curvature radius and display size on visual search accuracy, visual search speed, and visual fatigue. Background Although the advantages of curved displays have been reported, little is known about the interactive effects of display curvature radius and size. Method Twenty-seven individuals performed visual search tasks at a viewing distance of 50 cm using eight configurations involving four display curvature radii (400R, 600R, 1200R, and flat) and two display sizes (33 '' and 50 ''). To simulate curved screens, five flat display panels were horizontally arranged with their centers concentrically repositioned following each display curvature radius. Results For accuracy, speed, and fatigue, 33 ''-600R and 50 ''-600R provided the best or comparable-to-best results, whereas 50 ''-flat provided the worst results. For accuracy and fatigue, 33 ''-flat was the second worst. The changes in the horizontal field of view and viewing angle due to display curvature as well as the association between effective display curvature radii and empirical horopter (loci of perceived equidistance) can explain these results. Conclusion The interactive effects of display curvature radius and size were evident for visual search performance and fatigue. Beneficial effects of curved displays were maintained across 33 '' and 50 '', whereas increasing flat display size from 33 '' to 50 '' was detrimental. Application For visual search tasks at a viewing distance of 50 cm, 33 ''-600R and 50 '' 600R displays are recommended, as opposed to 33 '' and 50 '' flat displays. Wide flat displays must be carefully considered for visual display terminal tasks.