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- Myung, Kyungjae
- Center for Genomic Integrity
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| DC Field | Value | Language |
|---|---|---|
| dc.citation.endPage | 7669 | - |
| dc.citation.number | 13 | - |
| dc.citation.startPage | 7664 | - |
| dc.citation.title | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | - |
| dc.citation.volume | 95 | - |
| dc.contributor.author | Myung, K | - |
| dc.contributor.author | Braastad, C | - |
| dc.contributor.author | He, DM | - |
| dc.contributor.author | Hendrickson, EA | - |
| dc.date.accessioned | 2023-12-22T12:36:03Z | - |
| dc.date.available | 2023-12-22T12:36:03Z | - |
| dc.date.created | 2020-01-31 | - |
| dc.date.issued | 1998-06 | - |
| dc.description.abstract | The KARP-1 (Ku86 Autoantigen Related Protein-1) gene, which is expressed from the human Ku86 autoantigen lotus, appears to play a role in mammalian DNA double-strand break repair as a regulator of the DNA-dependent protein kinase complex. Here, we demonstrate that KARP-1 gene expression is significantly up-regulated following exposure of cells to DNA damage. KARP-1 mRNA induction was completely dependent on the ataxia telangiectasia and p53 gene products, consistent with the presence of a p53 binding site within the second intron of the KARP-1 locus, These observations link ataxia telangiectasia, p53, and KARP-1 in a common pathway. | - |
| dc.identifier.bibliographicCitation | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.95, no.13, pp.7664 - 7669 | - |
| dc.identifier.doi | 10.1073/pnas.95.13.7664 | - |
| dc.identifier.issn | 0027-8424 | - |
| dc.identifier.scopusid | 2-s2.0-0032560473 | - |
| dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/31100 | - |
| dc.identifier.url | https://www.pnas.org/content/95/13/7664 | - |
| dc.identifier.wosid | 000074436400077 | - |
| dc.language | 영어 | - |
| dc.publisher | NATL ACAD SCIENCES | - |
| dc.title | KARP-1 is induced by DNA damage in a p53- and ataxia telangiectasia mutated-dependent fashion | - |
| dc.type | Article | - |
| dc.description.isOpenAccess | FALSE | - |
| dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
| dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
| dc.type.docType | Article | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.subject.keywordPlus | DOUBLE-STRAND BREAKS | - |
| dc.subject.keywordPlus | V(D)J RECOMBINATION | - |
| dc.subject.keywordPlus | IONIZING-RADIATION | - |
| dc.subject.keywordPlus | CELLULAR-RESPONSE | - |
| dc.subject.keywordPlus | BINDING SITE | - |
| dc.subject.keywordPlus | INDUCTION | - |
| dc.subject.keywordPlus | GENE | - |
| dc.subject.keywordPlus | GROWTH | - |
| dc.subject.keywordPlus | REPAIR | - |
| dc.subject.keywordPlus | MUTATIONS | - |
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