BROWSE

Related Researcher

Author's Photo

Ryu, Ja-Hyoung
Supramolecular NanoMaterials Lab (SUN)
Research Interests
  • Supramolecular assembly, synthetic peptide assembly, cancer drug delivery

ITEM VIEW & DOWNLOAD

Supramolecular protection-mediated one-pot synthesis of cationic gold nanoparticles

Cited 0 times inthomson ciCited 0 times inthomson ci
Title
Supramolecular protection-mediated one-pot synthesis of cationic gold nanoparticles
Author
Jana, BatakrishnaKim, SeongchanChoi, HuyeonJin, SeongeonKim, KibeomKim, MinsooLee, HyojinLee, Kwan HyiLee, JungminPark, Myoung-HwanJeong, YoungdoRyu, Ja-HyoungKim, Chaekyu
Issue Date
2020-01
Publisher
한국공업화학회
Citation
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.81, pp.303 - 308
Abstract
Despite the extended use of cationic gold nanoparticles (AuNPs) in biomedical applications, direct one-pot synthesis of AuNPs with tunable size in aqueous media is limited due to the deleterious electrostatic attraction between AuCl4-anions and positively charged ligands. This paper describes the one-pot synthesis of cationic gold nanoparticles with size tunability based on host-guest chemistry. As the host molecule, cucurbit[7]uril inhibits self-aggregation in aqueous solution by threading positively charged guest ligands, which provides a shielding effect on the ligands. Reduction of the mixtures by directly adding NaBH4 generates cationic AuNPs with narrow size distributions. Furthermore, their potential in biomedical applications is demonstrated by siRNA transfection experiments. This approach relying on supramolecular-mediated interactions may provide new insights into organic/inorganic reactions that involve electrostatic disturbance.
URI
https://scholarworks.unist.ac.kr/handle/201301/27782
URL
https://www.sciencedirect.com/science/article/pii/S1226086X19304964
DOI
10.1016/j.jiec.2019.09.018
ISSN
1226-086X
Appears in Collections:
CHM_Journal Papers
Files in This Item:
There are no files associated with this item.

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU