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Takayama, Shuichi
Cell and Microfluidics Lab
Research Interests
  • Bio-MEMS and Microfluidics

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Next-generation integrated microfluidic circuits

Cited 19 times inthomson ciCited 19 times inthomson ci
Title
Next-generation integrated microfluidic circuits
Author
Mosadegh, BobakBersano-Begey, TommasoPark, Joong YullBurns, Mark A.Takayama, Shuichi
Keywords
LARGE-SCALE INTEGRATION; FLOW-CONTROL; VALVES; DEVICES; CHANNELS; DESIGN; MEMORY; LOGIC; PUMPS
Issue Date
2011-09
Publisher
ROYAL SOC CHEMISTRY
Citation
LAB ON A CHIP, v.11, no.17, pp.2813 - 2818
Abstract
This mini-review provides a brief overview of recent devices that use networks of elastomeric valves to minimize or eliminate the need for interconnections between microfluidic chips and external instruction lines that send flow control signals. Conventional microfluidic control mechanisms convey instruction signals in a parallel manner such that the number of instruction lines must increase as the number of independently operated valves increases. The devices described here circumvent this "tyranny of microfluidic interconnects" by the serial encoding of information to enable instruction of an arbitrary number of independent valves with a set number of control lines, or by the microfluidic circuit-embedded encoding of instructions to eliminate control lines altogether. Because the parallel instruction chips are the most historical and straightforward to design, they are still the most commonly used approach today. As requirements for instruction complexity, chip-to-chip communication, and real-time on-chip feedback flow control arise, the next generation of integrated microfluidic circuits will need to incorporate these latest interconnect flow control approaches
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DOI
10.1039/c1lc20387h
ISSN
1473-0197
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SLS_Journal Papers
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