BROWSE

Related Researcher

Author's Photo

Cha, Chaenyung
Integrative Biomaterials Engineering
Research Interests
  • Biomaterials, nanocomposites, microfabrication, tissue engineering, drug delivery

ITEM VIEW & DOWNLOAD

Cellulose acetate nanoneedle array covered with phosphorylcholine moiety as a biocompatible and sustainable antifouling material

Cited 0 times inthomson ciCited 0 times inthomson ci
Title
Cellulose acetate nanoneedle array covered with phosphorylcholine moiety as a biocompatible and sustainable antifouling material
Author
Park, Hyun-HaSun, KahyunLee, DongjinSeong, MinhoCha, ChaenyungJeong, Hoon Eui
Issue Date
2019-11
Publisher
SPRINGER
Citation
CELLULOSE, v.26, no.16, pp.8775 - 8788
Abstract
Extensive efforts have been devoted toward developing antibiofilm materials that can efficiently suppress bacterial attachment and subsequent biofilm formation. However, many of the previous approaches are based on non-biocompatible, non-degradable, and environmentally harmful synthetic materials. Herein, we report an efficient and sustainable biofilm-resistant material that is made of a biocompatible, biodegradable, and naturally abundant cellulose derivate biopolymer. The biofilm-resistant material is made of cellulose acetate (CA) and possesses precisely defined nanoscale needle-like architectures on its surface. The CA nanoneedle array is further coated with a cell-membrane mimicking monomer of 2-methacryloryloxyethyl phosphorylcholine (MPC). Based on the synergetic integration of the bio- and environment-friendly polymers of CA and MPC into nanoscale topography, the nanostructured CA not only effectively prevents bacterial attachment but also simultaneously exhibits strong bactericidal effects against both gram-positive and gram-negative bacteria. This natural cellulose derivative-based nanostructured material has strong potential as a biocompatible, and eco-friendly antibiofilm material for versatile uses in biomedical and industrial applications.
URI
https://scholarworks.unist.ac.kr/handle/201301/27389
URL
https://link.springer.com/article/10.1007%2Fs10570-019-02681-w
DOI
10.1007/s10570-019-02681-w
ISSN
0969-0239
Appears in Collections:
MSE_Journal Papers
MNE_Journal Papers
Files in This Item:
There are no files associated with this item.

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU