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Kim, Taesung
Microfluidics & Nanomechatronics Lab (μFNM)
Research Interests
  • Micro-/Nanofluidics

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Microfluidic Technologies for Synthetic Biology

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Title
Microfluidic Technologies for Synthetic Biology
Author
Vinuselvi, ParisuthamPark, SeongyongKim, MinseokPark, Jung MinKim, TaesungLee, Sung Kuk
Keywords
microfluidics; synthetic biology; genetic circuits; gene expression and regulation; metabolite detection; whole-cell analysis
Issue Date
2011-06
Publisher
MDPI AG
Citation
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.12, no.6, pp.3576 - 3593
Abstract
Microfluidic technologies have shown powerful abilities for reducing cost, time, and labor, and at the same time, for increasing accuracy, throughput, and performance in the analysis of biological and biochemical samples compared with the conventional, macroscale instruments. Synthetic biology is an emerging field of biology and has drawn much attraction due to its potential to create novel, functional biological parts and systems for special purposes. Since it is believed that the development of synthetic biology can be accelerated through the use of microfluidic technology, in this review work we focus our discussion on the latest microfluidic technologies that can provide unprecedented means in synthetic biology for dynamic profiling of gene expression/regulation with high resolution, highly sensitive on-chip and off-chip detection of metabolites, and whole-cell analysis.
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DOI
10.3390/ijms12063576
ISSN
1422-0067
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MNE_Journal Papers
ECHE_Journal Papers
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