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Myung, Kyungjae
Center for Genomic Integrity
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dc.citation.endPage 195 -
dc.citation.number 3 -
dc.citation.startPage 190 -
dc.citation.title TRANSCRIPTION-AUSTIN -
dc.citation.volume 9 -
dc.contributor.author Lee, Deokjae -
dc.contributor.author Park, Jun Hong -
dc.contributor.author Kim, Shinseog -
dc.contributor.author Lee, Seon-gyeong -
dc.contributor.author Myung, Kyungjae -
dc.date.accessioned 2023-12-21T21:13:05Z -
dc.date.available 2023-12-21T21:13:05Z -
dc.date.created 2018-06-19 -
dc.date.issued 2018-01 -
dc.description.abstract There are hundreds of copies of rDNA repeats in mammalian chromosomes and the ratio of active, poised, or inactive rDNA is regulated in epigenetic manners. Recent studies demonstrated that a post-DNA replication repair enzyme, SHPRH affects rRNA transcription by recognizing epigenetic markers on rDNA promoters and unveiled potential links between DNA repair and ribosome biogenesis. This study suggests that SHPRH could be a link between mTOR-mediated epigenetic regulations and rRNA transcription, while concomitantly affecting genomic integrity. -
dc.identifier.bibliographicCitation TRANSCRIPTION-AUSTIN, v.9, no.3, pp.190 - 195 -
dc.identifier.doi 10.1080/21541264.2017.1381795 -
dc.identifier.issn 2154-1264 -
dc.identifier.scopusid 2-s2.0-85045841854 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/24526 -
dc.identifier.url https://www.tandfonline.com/doi/full/10.1080/21541264.2017.1381795 -
dc.language 영어 -
dc.publisher TAYLOR & FRANCIS INC -
dc.title SHPRH as a new player in ribosomal RNA transcription and its potential role in homeostasis of ribosomal DNA repeats -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.description.journalRegisteredClass scopus -
dc.subject.keywordAuthor mTOR -
dc.subject.keywordAuthor plant homeodomain -
dc.subject.keywordAuthor ribosomal RNA -
dc.subject.keywordAuthor SHPRH -
dc.subject.keywordAuthor transcription -

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