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- Kang, Hyun-Wook
- 3D Biofabrication Lab.
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Turn-on and Turn-off Fluorescent Probes for Carbon Monoxide Detection and Blood Carboxyhemoglobin Determination
- Author(s)
- Shi, Genggongwo, Yoon, Taeseung, Cha, Seoncheol, Kim, Seulgi, Yousuf, Muhammad, Ahmed, Nisar, Kim, Doseok, Kang, Hyun-Wook, Kim, Kwang S.
- Issued Date
- 2018-06
- Citation
- ACS SENSORS, v.3, no.6, pp.1102 - 1108
- Abstract
- Water-soluble, carbazole-based two-photon excitable fluorescent probes MPVC-I ("turn-on") and MPVC-II ("turn-off") are rationally designed and synthesized for the selective monitoring of carbon monoxide (CO). Both probes can effectively measure carboxyhemoglobin (HbCO) in the blood of the animals exposed to a CO dose as low as 100 ppm for 10 min. The palladium catalyzed azidocarbonylation reaction was optimized to improve the sensing efficiency.
- Publisher
- AMER CHEMICAL SOC
- ISSN
- 2379-3694
- Keyword (Author)
- fluorescent probe, carbon monoxide, blood carboxyhemoglobin, gas sensing, azidocarbonylation
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