BROWSE

Related Researcher

Author's Photo

Lim, Mi Hee
MetalloNeuroChemistry Lab (MNCL)
Research Interests
  • Neurodegenerative disease, small molecule design, network between metal, proteins, and ROS

ITEM VIEW & DOWNLOAD

A single fluorescent chemosensor for multiple targets of Cu2+, Fe2+/3(+) and Al3+ in living cells and a near-perfect aqueous solution

Cited 0 times inthomson ciCited 0 times inthomson ci
Title
A single fluorescent chemosensor for multiple targets of Cu2+, Fe2+/3(+) and Al3+ in living cells and a near-perfect aqueous solution
Author
Jo, Tae GeunJung, Jae MinHan, JiyeonLim, Mi HeeKim, Cheal
Issue Date
2017-05
Publisher
ROYAL SOC CHEMISTRY
Citation
RSC ADVANCES, v.7, no.46, pp.28723 - 28732
Abstract
A sulfonate-based chemosensor 1 was designed and synthesized for sensing various analytes: Cu2+, Fe2+/3+ and Al3+. Sensor 1 showed a high selectivity and sensitivity for the analytes in a near-perfect aqueous medium. Cu2+ and Fe2+/(3+) could be monitored by fluorescence quenching of 1. It had sufficiently low detection limits (1.25 mu M for Cu2+ and 3.96 mu M for Fe3+), which were below the recommended levels of the World Health Organization for Cu2+ (31.5 mu M) and the Environmental Protection Agency for Fe3+ (5.37 mu M). 1 showed the high preferential selectivity for Cu2+ and Fe3+ in the presence of competitive metal ions without any interference. Importantly, pyrophosphate could be used to distinguish Fe3+ from Cu2+. In addition, this sensor could monitor Al3+ through fluorescence emission change. Moreover, 1 was successfully applied to quantify and image Al3+ in water samples and living cells. Based on photophysical studies and theoretical calculations, the sensing mechanisms of 1 for Cu2+ and Al3+ were explained, respectively.
URI
https://scholarworks.unist.ac.kr/handle/201301/22297
URL
http://pubs.rsc.org/en/Content/ArticleLanding/2017/RA/C7RA05565J#!divAbstract
DOI
10.1039/c7ra05565j
ISSN
2046-2069
Appears in Collections:
SNS_Journal Papers
Files in This Item:
000403012700019.pdf Download

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU