File Download

There are no files associated with this item.

  • Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
Related Researcher

정두영

Jung, Dooyoung
Healthcare Lab.
Read More

Views & Downloads

Detailed Information

Cited time in webofscience Cited time in scopus
Metadata Downloads

Longitudinal Association of Poor Sleep Quality With Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer

Author(s)
Jung, DooyoungLee, Kwang-MinKim, Win-HyoungLee, Joo-YoungKim, Tae-YongIm, Seok-AhLee, Kyung-HunSpiegel, DavidHahm, Bong-Jin
Issued Date
2016-10
DOI
10.1097/PSY.0000000000000372
URI
https://scholarworks.unist.ac.kr/handle/201301/20732
Fulltext
http://journals.lww.com/psychosomaticmedicine/Abstract/2016/10000/Longitudinal_Association_of_Poor_Sleep_Quality.10.aspx
Citation
PSYCHOSOMATIC MEDICINE, v.78, no.8, pp.959 - 965
Abstract
Objective: Risk factors for chemotherapy-induced nausea and vomiting (CINV) include older age, female sex, alcohol consumption, and a history of motion sickness. Although gastrointestinal symptoms are found to be related with sleep and mood in other conditions, little is known about their effects on CINV.
Methods: This prospective observational study recruited patients with early-stage breast cancer who had recovered from surgery before receiving a first cycle of anthracycline and cyclophosphamide-based chemotherapy. Candidate factors associated with CINV were assessed before chemotherapy by using the following: the Pittsburgh Sleep Quality Index, the Insomnia Severity Index, the Epworth Sleepiness Scale, and the Hospital Anxiety and Depression Scale. Chemotherapy-induced nausea (CIN) and chemotherapy-induced vomiting (CIV) were defined according to a numeric rating scale (0-10) as follows: >=3, nausea; >=1, vomiting.
Results: Between February 2012 and May 2014, data were collected from 198 patients. Chemotherapy-induced nausea occurred in 35.4% of patients, and CIV occurred in 31.3%. Chemotherapy-induced nausea was significantly associated with poor sleep quality (odds ratio [OR], 2.48; 95% confidence interval [CI], 1.13-5.46; p = 0.024) and pretreatment nausea (OR, 4.81; 95% CI, 1.84-12.62; p = 0.001). Likewise, CIV was significantly associated with poor sleep quality (OR, 2.64; 95% CI, 1.21-5.78; p = 0.015) and pretreatment nausea (OR, 3.07; 95% CI, 1.23-7.66; p = 0.016).
Conclusions: Poor sleep quality increases risk of CINV in patients with breast cancer. Sleep problems should be assessed and considered in the management of CINV.
Publisher
LIPPINCOTT WILLIAMS & WILKINS
ISSN
0033-3174
Keyword (Author)
chemotherapy-induced nausea and vomitingchemotherapy-induced nauseachemotherapy-induced vomitingsleepmoodbreast cancer
Keyword
GENERAL-POPULATIONDELAYED NAUSEARISK-FACTORSINSOMNIADEPRESSIONSCALEDOXORUBICINPREVALENCEVALIDATIONPREDICTION

qrcode

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.