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Kang, Sebyung
Protein Nanobio Lab
Research Interests
  • Protein engineering, Drug/diagnostics delivery nanoplatform, Protein-based vaccine delivery systems, Biosensor & imaging

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Genetically engineering encapsulin protein cage nanoparticle as a SCC-7 cell targeting optical nanoprobe

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dc.contributor.author Moon, Hyojin ko
dc.contributor.author Lee, Jisu ko
dc.contributor.author Kim, Hansol ko
dc.contributor.author Heo, Somin ko
dc.contributor.author Min, Junseon ko
dc.contributor.author Kang, Sebyung ko
dc.date.available 2016-10-17T02:27:01Z -
dc.date.created 2016-10-13 ko
dc.date.issued 2014-11 ko
dc.identifier.citation BIOMATERIALS RESEARCH, v.18, pp.21 ko
dc.identifier.issn 2055-7124 ko
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/20623 -
dc.description.abstract Background - Protein cage nanoparticles are promising nanoplatform candidates for efficient delivery systems of diagnostics and/or therapeutics because of their uniform size and structure as well as high biocompatibility and biodegradability. Encapsulin protein cage nanoparticle is used to develop a cell-specific targeting optical nanoprobe. Results - FcBPs are genetically inserted and successfully displayed on the surface of encapsulin to form FcBP-encapsulin. Selectively binding of FcBP-encapsulin to SCC-7 is visualized with fluorescent microscopy. Conclusions - Encapsulin protein cage nanoparticle is robust enough to maintain their structure at high temperature and easily acquires multifunctions on demand through the combination of genetic and chemical modifications. ko
dc.description.statementofresponsibility open -
dc.language 영어 ko
dc.publisher 한국생체재료학회 ko
dc.title Genetically engineering encapsulin protein cage nanoparticle as a SCC-7 cell targeting optical nanoprobe ko
dc.type ARTICLE ko
dc.identifier.scopusid 2-s2.0-85001159259 ko
dc.type.rims ART ko
dc.identifier.doi 10.1186/2055-7124-18-21 ko
dc.identifier.url https://biomaterialsres.biomedcentral.com/articles/10.1186/2055-7124-18-21 ko
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