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Jung, Woonggyu
Translational Biophotonics Laboratory (TBL)
Research Interests
  • Translational optical imaging, optical stimulation, multi-scale imaging, neuro-photonics, mobile-based medical device

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Preliminary Study of Optical Coherence Tomography Imaging to Identify Microscopic Extrathyroidal Extension in Patients With Papillary Thyroid Carcinoma

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Title
Preliminary Study of Optical Coherence Tomography Imaging to Identify Microscopic Extrathyroidal Extension in Patients With Papillary Thyroid Carcinoma
Author
Lee, Hyoung ShinShin, Sung WonBae, Jung KweonJung, WoonggyuKim, Sung WonOak, ChulhoChun, Bong KwonAhn, Yeh-ChanLee, Byung-JooLee, Kang Dae
Issue Date
2016-04
Publisher
WILEY-BLACKWELL
Citation
LASERS IN SURGERY AND MEDICINE, v.48, no.4, pp.371 - 376
Abstract
Background and ObjectivesWe evaluated the feasibility of using optical coherence tomography (OCT), to identify microscopic extrathyroidal extension (mETE) in ex vivo thyroidectomy specimens of patients who underwent thyroidectomy for the treatment of papillary thyroid carcinoma (PTC). MethodsA total of 170 ex vivo OCT images of the tumor, were acquired just after completion of thyroidectomy in 17 patients. The OCT images of each patient were separately evaluated by two blinded investigators, and the outcomes were compared with the histopathology reports. ResultsThe sensitivity and specificity of mETE identification from the OCT images were 81.4% and 86.0%, respectively, for the first investigator, and 82.9% and 87.0%, respectively, for the second investigator. Substantial agreement between the investigators was verified by Cohen's (Cohen's =0.772). ConclusionIn this preliminary study of a limited series of ex vivo thyroidectomy specimens, we verified the feasibility of OCT as a method of identifying mETE in patients with PTC. Lasers Surg. Med. 48:371-376, 2016.
URI
https://scholarworks.unist.ac.kr/handle/201301/18140
URL
http://onlinelibrary.wiley.com/doi/10.1002/lsm.22466/abstract
DOI
10.1002/lsm.22466
ISSN
0196-8092
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