BROWSE

Related Researcher

Author's Photo

Kim, Taesung
Microfluidics & Nanomechatronics Lab (μFNM)
Research Interests
  • Micro-/Nanofluidics
  • BioMEMS
  • Nanomechatronics

ITEM VIEW & DOWNLOAD

Crack-photolithography for Membrane-free Diffusion-based Micro/Nanofluidic Devices

Cited 0 times inthomson ciCited 0 times inthomson ci
Title
Crack-photolithography for Membrane-free Diffusion-based Micro/Nanofluidic Devices
Author
Kim, MinseokKim, Taesung
Issue Date
2015-11
Publisher
AMER CHEMICAL SOC
Citation
ANALYTICAL CHEMISTRY, v.87, no.22, pp.11215 - 11223
Abstract
Recent advances in controlling the cracking phenomena established a novel unconventional fabrication technique to generate mixed-scale patterns/structures with resolution and accuracy comparable to conventional nanofabrication techniques. Here, we adapt our previous cracking-assisted nanofabrication technique (called “crack-photolithography”) relying on only the standard photolithography to develop micro/nanofluidic devices with greatly reduced time and cost. The crack-photolithography makes it possible not only to simultaneously produce micropatterns and nanopatterns with various dimensions but also to replicate both of the mixed-scale patterns in a high-throughput manner. Therefore, a microfluidic channel network can easily be fabricated with a nanochannel array that can function as a nanoporous membrane wherever necessary, which basically plays a key role in diffusion-allowed but convection-suppressed microfluidic devices. In addition, the nanochannel array can manipulate the transport of small molecules by adjusting its dimension and/or number at will, so that nanochannel-array-integrated micro/nanofluidic devices prove even more robust and accurate in diffusion control than conventional membrane-integrated microfluidic devices. As an application of such micro/nanofluidic devices, we employed synthetic bacterial cells and found that their genetic induction and expression are dominated by extracellular diffusive microenvironments that were completely engineered using the nanochannel array. Hence, the crack-photolithography could provide innovative fabrication techniques for unprecedented micro/nanofluidic devices that show substantial potential for a wide range of biological and chemical applications.
URI
https://scholarworks.unist.ac.kr/handle/201301/17661
URL
http://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b02028
DOI
10.1021/acs.analchem.5b02028
ISSN
0003-2700
Appears in Collections:
MEN_Journal Papers
Files in This Item:
There are no files associated with this item.

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU