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Bhak, Jong
KOrean GenomIcs Center(KOGIC)
Research Interests
  • Geromics, genomics, bioinformatics, protein Engineering, OMICS

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Genetic dating indicates that the Asian-Papuan admixture through Eastern Indonesia corresponds to the Austronesian expansion

Cited 22 times inthomson ciCited 21 times inthomson ci
Title
Genetic dating indicates that the Asian-Papuan admixture through Eastern Indonesia corresponds to the Austronesian expansion
Author
Xu, ShuhuaPugach, IrinaStoneking, MarkKayser, ManfredJin, LiBhak, Jong HwaAbdulla, Mahmood AmeenAhmed, IkhlakAssawamakin, AnunchaiBrahmachari, Samir K.Calacal, Gayvelline C.Chaurasia, AmitChen, Chien-HsiunChen, JiemingChen, Yuan-TsongChu, Jiayoude la Paz, Eva Maria c.Ungria, Maria Corazon A.Delfin, Frederick C.Edo, JuliFuchareonc, SuthatGhang, HoGojobori, TakashiHan, JunsongHo, Sheng-FengHoh, Boon PengHuang, WeiInoko, HidetoshiJha, PankajJinam, Timothy A.Jin, LiJung, JongsunKangwanpong, DaoroongKampuansai, JatupolKennedy, Giulia C.Khurana, PreetiKim, Hyung-LaeKim, KwangjoongKim, SangsooKim, Woo-YeonKimm, KuchanKimura, RyosukeKoike, TomohiroKulawonganunchai, SupasakKumar, VikrantLai, Poh SanLee, Jong-YoungLee, SunghoonLiu, Edison T.Majumder, Partha P.Mandapati, Kiran KumarMarzuki, SangkotMitchell, WayneMukerji, MitaliNaritomi, KenjiNgamphiw, ChumpolNiikawa, NorioNishida, NaoOh, BermseokOh, SanghoOhashi, JunOka, AkiraOng, RickPadilla, Carmencita D.Palittapongarnpim, PrasitPerdigon, Henry B.Phipps, Maude ElviraPng, EileenSakaki, YoshiyukiSalvador, Jazelyn M.Sandraling, YulianaScaria, VinodSeielstad, MarkSidek, Mohd RosSinha, AmitSrikummool, MetaweeSudoyo, HerawatiSugano, SumioSuryadi, HelenaSuzuki, YoshiyukiTabbada, Kristina A.Tan, AdrianTokunaga, KatsushiTongsiam, SissadesVillamor, Lilian P.Wang, EricWang, YingWang, HaifengWu, Jer-YuarnXiao, HuashengXu, ShuhuaYang, Jin OkShugart, Yin YaoYoo, Hyang-SookYuan, WentaoZhao, GuopingZilfalil, Bin Alwi
Keywords
Admixture time; Expansion time; Migration rate; Single nucleotide polymorphism
Issue Date
2012-03
Publisher
NATL ACAD SCIENCES
Citation
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.109, no.12, pp.4574 - 4579
Abstract
Although the Austronesian expansion had a major impact on the languages of Island Southeast Asia, controversy still exists over the genetic impact of this expansion. The coexistence of both Asian and Papuan genetic ancestry in Eastern Indonesia provides a unique opportunity to address this issue. Here, we estimate recombination breakpoints in admixed genomes based on genome-wide SNP data and date the genetic admixture between populations of Asian vs. Papuan ancestry in Eastern Indonesia. Analyses of two genome-wide datasets indicate an eastward progression of the Asian admixture signal in Eastern Indonesia beginning about 4,000-3,000 y ago, which is in excellent agreement with inferences based on Austronesian languages. The average rate of spread of Asian genes in Eastern Indonesia was about 0.9 km/y. Our results indicate that the Austronesian expansion had a strong genetic as well as linguistic impact on Island Southeast Asia, and they significantly advance our understanding of the biological origins of human populations in the Asia-Pacific region
URI
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DOI
10.1073/pnas.1118892109
ISSN
0027-8424
Appears in Collections:
BME_Journal Papers
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