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Suh, Pann-Ghill
BioSignal Network Lab (BSN)
Research Interests
  • Signal transduction, cancer, metabolism, phospholipase C

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Enhanced expression of neuronal nitric oxide synthase and phospholipase C-gamma 1 in regenerating murine neuronal cells by pulsed electromagnetic field

Cited 27 times inthomson ciCited 28 times inthomson ci
Title
Enhanced expression of neuronal nitric oxide synthase and phospholipase C-gamma 1 in regenerating murine neuronal cells by pulsed electromagnetic field
Author
Kim, Sung SookShin, Hye JungEom, Dae WoonHuh, Joo RyungWoo, YeongjuKim, HyokyungRyu, Sung HoSuh, Pann-GhillKim, Moon JungKim, Jee YunKoo, Tae WanCho, Yoon HeeChung, Sung Min
Keywords
NOS; PEMF; PLC-γ1; S-100
Issue Date
2002-03
Publisher
KOREAN SOC MED BIOCHEMISTRY MOLECULAR BIOLOGY
Citation
EXPERIMENTAL AND MOLECULAR MEDICINE, v.34, no.1, pp.53 - 59
Abstract
Pulsed electromagnetic field (PEMF) has been shown to improve the rate of peripheral nerve regeneration. In the present study we investigated the expression of neuronal nitric oxide synthase (nNOS) and phospholipase C-gamma1 (PLC-gamma1) in regenerating rat laryngeal nerves during the exposure to PEMF after surgical transection and reanastomosis. Axons were found to regenerate into the distal stump nearly twice faster in PEMF-exposed animals than in the control. Consistently, motor function was better recovered in PEMF-treated rats. The expression of nNOS and PLC-gamma1 was highly enhanced in the regenerated nerves
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DOI
10.1038/emm.2002.8
ISSN
1226-3613
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BME_Journal Papers
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