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Kang, Hyun-Wook
3D Biofabrication Lab (3BL)
Research Interests
  • 3D Bioprinting, tissue engineering and regenerative medicine, Body-on-a-chip

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Development of a scaffold fabrication system using an axiomatic approach

Cited 29 times inthomson ciCited 17 times inthomson ci
Title
Development of a scaffold fabrication system using an axiomatic approach
Other Titles
Development of a scaffold fabrication system using an axiomatic approach
Author
Lee, Seung-JaeKang, Hyun-WookKang, Tae-yeunKim, ByungLim, GeunbaeRhie, Jong-WonCho, Dong-Woo
Keywords
MICRO-STEREOLITHOGRAPHY TECHNOLOGY;  ARCHITECTURES;  CARTILAGE 저자 정보
Issue Date
2007-01
Publisher
IOP PUBLISHING LTD
Citation
JOURNAL OF MICROMECHANICS AND MICROENGINEERING, v.17, no.1, pp.147 - 153
Abstract
To generate complex cartilage/bone tissues, scaffolds must possess several structural features that are difficult to create using conventional scaffold design/fabrication technologies. Successful cartilage/bone regeneration depends on the ability to assemble chondrocytes/osteoblasts into three-dimensional ( 3D) scaffolds. Therefore, we developed a 3D scaffold fabrication system that applies the axiomatic approach to our microstereolithography system. The new system offers a reduced machine size by minimizing the optical components, and shows that the design matrix is decoupled. This analysis identified the key factors affecting microstructure fabrication and an improved scaffold fabrication system was constructed. The results demonstrate that precise, predesigned 3D structures can be fabricated. Using this 3D scaffold, cell adhesion behavior was observed. The use of 3D scaffolds might help determine key factors in the study of cell behavior in complex environments and could eventually lead to the optimal design of scaffolds for the regeneration of various tissues, such as cartilage and bone
URI
https://scholarworks.unist.ac.kr/handle/201301/13350
DOI
10.1088/0960-1317/17/1/019
ISSN
0960-1317
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BME_Journal Papers
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