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Bhak, Jong
KOrean GenomIcs Center(KOGIC)
Research Interests
  • Geromics, genomics, bioinformatics, protein Engineering, OMICS

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HPID: The Human Protein Interaction Database

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Title
HPID: The Human Protein Interaction Database
Other Titles
HPID: The Human Protein Interaction Database
Author
Han, KyungsookPark, ByungkyuKim, HyongguenHong, JinsunBhak, Jong Hwa
Keywords
INTERACTION MAP; YEAST; PDB
Issue Date
2004-10
Publisher
OXFORD UNIV PRESS
Citation
BIOINFORMATICS, v.20, no.15, pp.2466 - 2470
Abstract
The Human Protein Interaction Database (http://www.hpid.org) was designed (1) to provide human protein interaction information pre-computed from existing structural and experimental data, (2) to predict potential interactions between proteins submitted by users and (3) to provide a depository for new human protein interaction data from users. Two types of interaction are available from the pre-computed data: (1) interactions at the protein superfamily level and (2) those transferred from the interactions of yeast proteins. Interactions at the superfamily level were obtained by locating known structural interactions of the PDB in the SCOP domains and identifying homologs of the domains in the human proteins. Interactions transferred from yeast proteins were obtained by identifying homologs of the yeast proteins in the human proteins. For each human protein in the database and each query submitted by users, the protein superfamilies and yeast proteins assigned to the protein are shown, along with their interacting partners. We have also developed a set of web-based programs so that users can visualize and analyze protein interaction networks in order to explore the networks further
URI
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DOI
10.1093/bioinformatics/bth253
ISSN
1367-4803
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BME_Journal Papers
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