BROWSE

Related Researcher

Author's Photo

Kim, Seong-Jin
Bio-inspired Microsystems Lab (BiML)
Research Interests
  • Integrated analog-mixed signal circuit design, semiconductor sensor interface circuits

ITEM VIEW & DOWNLOAD

Real-time label-free quantitative monitoring of biomolecules without surface binding by floating-gate complementary metal-oxide semiconductor sensor array integrated with readout circuitry

Cited 2 times inthomson ciCited 3 times inthomson ci
Title
Real-time label-free quantitative monitoring of biomolecules without surface binding by floating-gate complementary metal-oxide semiconductor sensor array integrated with readout circuitry
Author
Kim, Seong-JinYoo, KyutaeShim, JeoyoungChung, WonseokKo, ChristopherIm, MaesoonKim, Lee-SupYoon, Euisik
Issue Date
2007-11
Publisher
AMER INST PHYSICS
Citation
APPLIED PHYSICS LETTERS, v.91, pp.203903
Abstract
We report a label-free field-effect sensing array integrated with complementary metal-oxide semiconductor (CMOS) readout circuitry to detect the surface potential determined by the negative charge in DNA molecules. For real-time DNA quantification, we have demonstrated the measurements of DNA molecules without immobilizing them on the sensing surface which is composed of an array of floating-gate CMOS transistors. This nonimmobilizing technique allows the continuous monitoring of the amount of charged molecules by injecting DNA solutions sequentially. We have carried out the real-time quantitative measurement of 19 bp oligonucleotides and analyzed its sensitivity as a function of pH in buffer solutions. (c) 2007 American Institute of Physics.
URI
https://scholarworks.unist.ac.kr/handle/201301/12383
URL
http://scitation.aip.org/content/aip/journal/apl/91/20/10.1063/1.2803848
DOI
10.1063/1.2803848
ISSN
0003-6951
Appears in Collections:
EE_Journal Papers
Files in This Item:
There are no files associated with this item.

find_unist can give you direct access to the published full text of this article. (UNISTARs only)

Show full item record

qrcode

  • mendeley

    citeulike

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

MENU