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Rhee, Hyun-Woo
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Selective fluorescent chemosensor for the bacterial alarmone (p)ppGpp

Alternative Title
Selective fluorescent chemosensor for the bacterial alarmone (p)ppGpp
Author(s)
Rhee, Hyun-WooLee, Chang-RoCho, Seung-HyonSong, Mi-RyungCashel, MichaelChoy, Hyon E.Seok, Young-JaeHong, Jong-In
Issued Date
2008-01
DOI
10.1021/ja0759139
URI
https://scholarworks.unist.ac.kr/handle/201301/12126
Fulltext
http://pubs.acs.org/doi/abs/10.1021/ja0759139
Citation
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.130, no.3, pp.784 - +
Abstract
We have developed the first selective fluorescent chemosensor (PyDPA) for (p)ppGpp, a bacterial and plant alarmone. By using pyrene-excimer fluorescence, PyDPA shows very good selectivity for (p)ppGpp from among other nucleotides in water. PyDPA was used for the real-time detection of in vitro ppGpp synthesis by bacterial ribosomal complexes
Publisher
AMER CHEMICAL SOC
ISSN
0002-7863
Keyword
GUANOSINE 5&apos-DIPHOSPHATE 3&apos-DIPHOSPHATEESCHERICHIA-COLIPYROPHOSPHATE SENSORTRANSCRIPTION REGULATIONINVITRO DEGRADATIONEXCIMER FORMATIONAQUEOUS-SOLUTIONPPGPPACCUMULATIONWATER

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