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Jung, Woonggyu
Translational Biophotonics Laboratory (TBL)
Research Interests
  • Translational optical imaging, optical stimulation, multi-scale imaging, neuro-photonics, mobile-based medical device

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Miniaturized probe based on a microelectromechanical system mirror for multiphoton microscopy

Cited 44 times inthomson ciCited 49 times inthomson ci
Title
Miniaturized probe based on a microelectromechanical system mirror for multiphoton microscopy
Author
Jung, WoonggyuTang, SuoMcCormic, Daniel T.Xie, TiquiangAhn, Yeh-ChanSu, JianpingTomov, Ivan V.Krasieva, Tatiana B.Tromberg, Bruce J.Chen, Zhongping
Keywords
biological specimens; Double-clad; Fluorescent beads; Fluorescent signals; High collection efficiency; Micro-electro- mechanical system (MEMS); Microelectromechanical system (MEMS) mirror; Multiphoton microscopy (MPM); Optical society of America (OSA); Outer diameter (OD); Photonic crystal fiber (PCF); Preclinical studies; Probe based; Short pulses; size reductions
Issue Date
2008-06
Publisher
OPTICAL SOC AMER
Citation
OPTICS LETTERS, v.33, no.12, pp.1324 - 1326
Abstract
A factor that limits the use of multiphoton microscopy (MFM) in clinical and preclinical studies is the lack of a compact and flexible probe. We report on a miniaturized MPM probe employing a microelectromechanical system (MEMS) scanning mirror and a double-clad photonic crystal fiber (DCPCF). The use of a MEMS mirror and a DCPCF provides many advantages, such as size reduction, rapid and precise scanning, efficient delivery of short pulses, and high collection efficiency of fluorescent signals. The completed probe was 1 cm in outer diameter and 14 cm in length. The developed probe was integrated into an MPM system and used to image fluorescent beads, paper, and biological specimens.
URI
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DOI
10.1364/OL.33.001324
ISSN
0146-9592
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BME_Journal Papers
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