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- Jung, Woonggyu
- Translational Biophotonics Lab.
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Miniaturized probe based on a microelectromechanical system mirror for multiphoton microscopy
- Author(s)
- Jung, Woonggyu, Tang, Suo, McCormic, Daniel T., Xie, Tiquiang, Ahn, Yeh-Chan, Su, Jianping, Tomov, Ivan V., Krasieva, Tatiana B., Tromberg, Bruce J., Chen, Zhongping
- Issued Date
- 2008-06
- Citation
- OPTICS LETTERS, v.33, no.12, pp.1324 - 1326
- Abstract
- A factor that limits the use of multiphoton microscopy (MFM) in clinical and preclinical studies is the lack of a compact and flexible probe. We report on a miniaturized MPM probe employing a microelectromechanical system (MEMS) scanning mirror and a double-clad photonic crystal fiber (DCPCF). The use of a MEMS mirror and a DCPCF provides many advantages, such as size reduction, rapid and precise scanning, efficient delivery of short pulses, and high collection efficiency of fluorescent signals. The completed probe was 1 cm in outer diameter and 14 cm in length. The developed probe was integrated into an MPM system and used to image fluorescent beads, paper, and biological specimens.
- Publisher
- OPTICAL SOC AMER
- ISSN
- 0146-9592
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