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Showing results 1 to 8 of 8

Issue DateTitleAuthor(s)TypeView
2018-10-20A novel TRAP1 inhibitor, containing flexible triphenylphosphonium, interacted with an allosteric site involving E403 residue and triggered protein conformational changesYoon, Nam Gu; Kang, Byoung HeonCONFERENCE52
2020-10-08A novel TRAP1 inhibitor, UB-010 potently inactivates the mitochondrial chaperoneby interacting with the client binding site.Yoon, Nam Gu; Hu, Sung; Kim. So-Yeon; Lee, Changwook; Kang, Byoung HeonCONFERENCE35
2017-04-03Chemical approaches to development of mitochondrial-targeted Hsp90 inhibitor as anti-cancer therapeutics: Mechanism and conformational change of mitochondrial Hsp90Hu, Sung; Yoon, Nam Gu; Kang, Byoung HeonCONFERENCE36
2020-08Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft modelsKim, Darong; Kim, So-Yeon; Kim, Dongyoung; Yoon, Nam Gu; Yun, Jisu; Hong, Ki Bum; Lee, Changwook; Lee, Ji Hoon; Kang, Byoung Heon; Kang, SoosungARTICLE95
2020-01Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1Jung, Sejin; Yoon, Nam Gu; Yang, Sujae; Kim, Darong; Lee, Won Seok; Hong, Ki Bum; Lee, Changwook; Kang, Byoung Heon; Lee, Ji Hoon; Kang, SoosungARTICLE149
2020-03Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting DrugHu, Sung; Ferraro, Mariarosaria; Thomas, Ajesh P.; Chung, Jeong Min; Yoon, Nam Gu; Seol, Ji-Hoon; Kim, Sangpil; Kim, Han-Ul; An, Mi Young; Ok, Haewon; Jung, Hyun Suk; Ryu, Ja-Hyoung; Colombo, Giorgio; Kang, Byoung HeonARTICLE111
2020-10-08Function of mitochondrial HSP90 in tumor angiogenesisKim, So Yeon; Yoon, Nam Gu; Kim, Eun Hye; Kang, Byoung HeonCONFERENCE35
2020-01Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1Park, Hye-Kyung; Yoon, Nam Gu; Lee, Ji-Eun; Hu, Sung; Yoon, Sora; Kim, So Yeon; Hong, Jun-Hee; Nam, Dougu; Chae, Young Chan; Park, Jong Bae; Kang, Byoung HeonARTICLE232
Showing results 1 to 8 of 8