| 2018-10-20 | A novel TRAP1 inhibitor, containing flexible triphenylphosphonium, interacted with an allosteric site involving E403 residue and triggered protein conformational changes | Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 287 |
| 2020-10-08 | A novel TRAP1 inhibitor, UB-010 potently inactivates the mitochondrial chaperoneby interacting with the client binding site. | Yoon, Nam Gu; Hu, Sung; Kim. So-Yeon; Lee, Changwook; Kang, Byoung Heon | CONFERENCE | 339 |
| 2022-02 | Anticancer strategy targeting the tumor microenvironment and development of potent TRAP1 inhibitors | Kang, Byoung Heon; Yoon, Nam Gu | Doctoral thesis | 1108 |
| 2017-04-03 | Chemical approaches to development of mitochondrial-targeted Hsp90 inhibitor as anti-cancer therapeutics: Mechanism and conformational change of mitochondrial Hsp90 | Hu, Sung; Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 301 |
| 2021-07 | Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity | Yang, Sujae; Yoon, Nam Gu; Kim, Dongyoung; Park, Eunsun; Kim, So-Yeon; Lee, Ji Hoon; Lee, Changwook; Kang, Byoung Heon; Kang, Soosung | ARTICLE | 339 |
| 2020-08 | Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models | Kim, Darong; Kim, So-Yeon; Kim, Dongyoung; Yoon, Nam Gu; Yun, Jisu; Hong, Ki Bum; Lee, Changwook; Lee, Ji Hoon; Kang, Byoung Heon; Kang, Soosung | ARTICLE | 397 |
| 2020-01 | Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1 | Jung, Sejin; Yoon, Nam Gu; Yang, Sujae; Kim, Darong; Lee, Won Seok; Hong, Ki Bum; Lee, Changwook; Kang, Byoung Heon; Lee, Ji Hoon; Kang, Soosung | ARTICLE | 487 |
| 2020-03 | Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting Drug | Hu, Sung; Ferraro, Mariarosaria; Thomas, Ajesh P.; Chung, Jeong Min; Yoon, Nam Gu; Seol, Ji-Hoon; Kim, Sangpil; Kim, Han-Ul; An, Mi Young; Ok, Haewon; Jung, Hyun Suk; Ryu, Ja-Hyoung; Colombo, Giorgio; Kang, Byoung Heon | ARTICLE | 539 |
| 2020-10-08 | Function of mitochondrial HSP90 in tumor angiogenesis | Kim, So Yeon; Yoon, Nam Gu; Kim, Eun Hye; Kang, Byoung Heon | CONFERENCE | 318 |
| 2021-12-10 | Function of mitochondrial HSP90 in tumor microenvironment | Kim, So Yeon; Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 473 |
| 2021-08-25 | Function of mitochondrial HSP90 in tumor micronenvironment | Kim, So Yeon; Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 176 |
| 2021-12-10 | MitoQ inactivates mitochondrial chaperone TRAP1 by interacting with the client binding site | Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 487 |
| 2021-12 | Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site | Yoon, Nam Gu; Lee, Hakbong; Kim, So-Yeon; Hu, Sung; Kim, Darong; Yang, Sujae; Hong, Ki Bum; Lee, Ji Hoon; Kang, Soosung; Kim, Byung-Gyu; Myung, Kyungjae; Lee, Changwook; Kang, Byoung Heon | ARTICLE | 470 |
| 2022-03 | Quaternary ammonium-based mitochondria targeting anticancer agents with high water solubility | Kim, Sangpil; Yoon, Nam Gu; Jana, Batakrishna; Kang, Byoung Heon; Ryu, Ja-Hyoung | ARTICLE | 158 |
| 2021-08-25 | SMx inactivates mitochondrial chaperone TRAP1 by interacting with the client binding site | Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 172 |
| 2022-02-17 | The mitochondrial HSP90 TRAP1 regulate hypoxic tumor microenvironment. | Kim, So Yeon; Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 64 |
| 2022-08-26 | The mitochondrial HSP90, TRAP1 regulates hypoxic environment via stability of HIF1α. | Kim, So Yeon; Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 54 |
| 2022-09 | Triphenylphosphonium conjugation to a TRAP1 inhibitor, 2-amino-6--chloro-7,9-dihydro-8H-purin-8-one increases antiproliferative activity | Yang, Sujae; Yoon, Nam Gu; Park, Min-A; Yun, Jisu; Im, Jin Young; Kang, Byoung Heon; Kang, Soosung | ARTICLE | 627 |
| 2020-01 | Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 | Park, Hye-Kyung; Yoon, Nam Gu; Lee, Ji-Eun; Hu, Sung; Yoon, Sora; Kim, So Yeon; Hong, Jun-Hee; Nam, Dougu; Chae, Young Chan; Park, Jong Bae; Kang, Byoung Heon | ARTICLE | 684 |
