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Analysis of mitochondrial membrane potential, ROS, and calcium File

Article Issue Date2025-08 View104

Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim File File

Park, Hye-Kyung , Lee, Ji-Eun , Lim, Jaehwa , Jo, Da-Eun , Park, Soo-Ah , Suh, Pann-Ghill , Kang, Byoung Heon

Article Issue Date2014-06 View247

Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 File

Lee, Changwook , Park, Hye-Kyung , Jeong, Hanbin , Lim, Jaehwa , Lee, An-Jung , Cheon, Keun Young , Kim, Chul-Su , Thomas, Ajesh P. , Bae, Boram , Kim, Nam Doo , et al

Article Issue Date2015-04 View191

Development of Hsp90 family protein inhibitors

Park, Hye-Kyung , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Jeong, Hanbin , Lee, An-Jung , Im, Jin Young , Kim, Seong Heon , Lee, Changwook , et al

Conference Paper Issue Date2016-12-09 View76

eIF2α phosphorylation-ATF4 axis-mediated transcriptional reprogramming mitigates mitochondrial impairment during ER stress File

Le, Hien Thi , Yu, Jiyoung , Ahn, Hee Sung , Kim, Mi-Jeong , Chae, In Gyeong , Cho, Hyun-Nam , Kim, Juhee , Park, Hye-Kyung , Kwon, Hyuk Nam , Chae, Han-Jung , et al

Article Issue Date2025-02 View53

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis File File

Choi, Sun Sil , Lee, Sang Kwon , Kim, Joong Kwan , Park, Hye-Kyung , Lee, Eujin , Jang, Jinho , Lee, Yo Han , Khim, Keon Woo , Hyun, Ji-Min , Eom, Hye-jin , et al

Article Issue Date2020-06 View212

Hepatocyte TonEBP promotes metabolic stress-induced hepatic fibroinflammation involving transcriptional activation of ELR+ CXC chemokines File File

Lee, Jun Ho , Song, Hana , Yoo, Eun Jin , Jeong, Yeseul , Ko, Seung Mi , Shin, Go Woon , Choi, Gee Euhn , Jee, Youngheun , Kang, Minhyeok , Yang, Jiwon , et al

Article Issue Date2026-02 View8

Hepatoprotective and antineoplastic properties of Protaetia brevitarsis larvae File

Lee, Ji-Eun , Jo, Da-Eun , Lee, An-Jung , Park, Hye-Kyung , Youn, Kumju , Yun, Eun-Young , Hwang, Jae-Sam , Jun, Mira , Kang, Byoung Heon

Article Issue Date2014-11 View148

HIF-1α/CypD Negative Regulation Accelerates Hypoxia-induced Cancer Metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-02-17 View84

Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells File

Park, Hye-Kyung , Hong, Jun-Hee , Oh, Young Taek , Kim, Sung Soo , Yin, Jinlong , Lee, An-Jung , Chae, Young Chan , Kim, Jong Heon , Park, Sung-Hye , Park, Chul-Kee , et al

Article Issue Date2019-04 View130

Loops of HIF1a and Cyclophilin D promote cancer netastasis through long-term ROS signaling.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2020-10-08 View62

Microenvironment-adapted mitochondria promote metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2023-05-08 View56

Mitochondria adapted to the microenvironment of primary tumors promote cancer metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2023-06-16 View69

Mitochondria target therapy through inhibition TRAP1-IDH2 to treat relapse/refractory acute myeloid leukemia

Sung Hu , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-02-16 View63

Mitochondria target therapy through inhibition TRAP1-IDH2 to treat relapse/refractory AML

Hu, Sung , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-08-26 View92

Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells File File

Park, Hye-Kyung , Lee, Ji-Eun , Lim, Jaehwa , Kang, Byoung Heon

Article Issue Date2014-06 View108

Mitochondrial regulation accelerates cancer Metastasis.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-09-29 View78

Overcoming Chemo-resistance through TRAP1 Inhibition Targeting High Mitochondrial Activity in Relapse/Refractory Acute Myeloid Leukemia

Hu, Sung , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2022-09-29 View71

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors File

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geumwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Im, Jin Young , Hu, Sung , Kim, Seong Heon , et al

Article Issue Date2017-09 View185

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors

Park, Hye-Kyung , Jeong, Hanbin , Ko, Eunhwa , Lee, Geunwoo , Lee, Ji-Eun , Lee, Sang Kwang , Lee, An-Jung , Lee, Jin Young , Hu, Sung , Kin, Seong Heon , et al

Conference Paper Issue Date2018-06-28 View81

Pro-survival function of the mitochondrial Hsp90 homolog, TRAP1, in cancer cells and insight into cancer therapy File File

Park, Hye-Kyung

Thesis Issue Date2015-02 View109

Pseudohypoxic stabilization of HIF1α via cyclophilin D suppression promotes melanoma metastasis File

Park, Hye-Kyung , Hu, Sung , Kim, So Yeon , Yoon, Sora , Yoon, Nam Gu , Lee, Ji Hye , Choi, Wonyoung , Kong, Sun-Young , Kim, Jong Heon , Nam, Dougu , et al

Article Issue Date2025-07 View130

Regulation of TRAP1 and SIRT3 in glioma stem cells

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2019-06-19 View71

ROS dependent HIF-1α and CypD negative feedback promotes hypoxia-induced cancer metastasis

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2021-12-10 View72

ROS dependent HIF-1α/CypD negative feedback promotes hypoxia-induced cancer metastasis.

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2021-08-25 View72

ROS regulation by Cyclophilin D contributes cancer metastasis via hypoxic signaling

Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2020-10-05 View53

Simultaneous inhibition of Hsp90 family proteins promotes apoptotic cell death via calcineurin activity

Park, Hye-Kyung , Noh, Dong Yeon , Kang, Byoung Heon

Conference Paper Issue Date2017-05-18 View64

TonEBP in Myeloid Cells Promotes Obesity-Induced Insulin Resistance and Inflammation Through Adipose Tissue Remodeling File File

Lee, Hwan Hee , Jeong, Gyu Won , Ye, Byeong Jin , Yoo, Eun Jin , Son, Keoung Sun , Kim, Dong Ki , Park, Hye-Kyung , Kang, Byoung Heon , Lee-Kwon, Whaseon , Kwon, Hyug Moo , et al

Article Issue Date2022-12 View179

TonEBP regulates ESR1 transcription and ER-dependent proliferation in ER-positive breast cancer File File

Kang, Hyun Je , Song, Hana , Park, Hyun , Park, Hye-Kyung , Shin, Go Woon , Son, Keoung Sun , Jeong, Yeseul , Ko, Seung Mi , Nam, Dougu , Kwon, Hyug Moo , et al

Article Issue Date2026-04 View9

Treatment Chemo-resistant Acute Myeloid Leukemia by Targeting Mitochondrial Activity

Hu, Sung , Park, Hye-Kyung , Kang, Byoung Heon

Conference Paper Issue Date2023-02-22 View69

Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 File File

Park, Hye-Kyung , Yoon, Nam Gu , Lee, Ji-Eun , Hu, Sung , Yoon, Sora , Kim, So Yeon , Hong, Jun-Hee , Nam, Dougu , Chae, Young Chan , Park, Jong Bae , et al

Article Issue Date2020-01 View173

장수풍뎅이 유충의 간보호 효능 및 항암활성 File File

Lee, Ji-Eun , Jo, Da-Eun , Lee, An-Jung , Park, Hye-Kyung , Youn, Kumju , Yun, Eun-Young , Hwang, Jae-Sam , Jun, Mira , Kang, Byoung Heon

Article Issue Date2015-03 View185

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