2018-10-20 | A novel TRAP1 inhibitor, containing flexible triphenylphosphonium, interacted with an allosteric site involving E403 residue and triggered protein conformational changes | Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 148 |
2020-10-08 | A novel TRAP1 inhibitor, UB-010 potently inactivates the mitochondrial chaperoneby interacting with the client binding site. | Yoon, Nam Gu; Hu, Sung; Kim. So-Yeon; Lee, Changwook; Kang, Byoung Heon | CONFERENCE | 189 |
2022-02 | Anticancer strategy targeting the tumor microenvironment and development of potent TRAP1 inhibitors | Kang, Byoung Heon; Yoon, Nam Gu | Doctoral thesis | 130 |
2002 | Caspase-3 has enhanced proteolytic properties at acidic pH | Kang, Byoung Heon | CONFERENCE | 115 |
2000-10 | Characterization of active-site residues of the NIa protease from tobacco vein mottling virus | Hwang, DC; Kim, DH; Lee, JS; Kang, Byoung Heon; Han, J; Kim, W; Song, BD; Choi, KY | ARTICLE | 902 |
1996-07 | Characterization of Nla protease from turnip mosaic potyvirus exhibiting a low-temperature optimum catalytic activity | Kim, DH; Hwang, D; Kang, Byoung Heon; Lew, J; Choi, KY | ARTICLE | 759 |
2017-05-18 | Chemical approaches to development of mitochondrial-targeted Hsp90 inhibitor as anti-cancer drug: Mechanism and conformational change of mitochondrial Hsp90 | Hu, Sung; Yoon, Nam gu; Jung, Hyun suck; Han, In cheol; Kang, Byoung Heon | CONFERENCE | 119 |
2017-04-03 | Chemical approaches to development of mitochondrial-targeted Hsp90 inhibitor as anti-cancer therapeutics: Mechanism and conformational change of mitochondrial Hsp90 | Hu, Sung; Yoon, Nam Gu; Kang, Byoung Heon | CONFERENCE | 145 |
2013 | Combination effect on Gamitrinib-TPP on tamoxifen-resistant breast cancer cell line | Kang, Byoung Heon; None; None | CONFERENCE | 120 |
2014-06 | Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim | Park, Hye-Kyung; Lee, Ji-Eun; Lim, Jaehwa; Jo, Da-Eun; Park, Soo-Ah; Suh, Pann-Ghill; Kang, Byoung Heon | ARTICLE | 1030 |
2009-03 | Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90 | Kang, Byoung Heon; Plescia, Janet; Song, Ho Young; Meli, Massimiliano; Colombo, Giorgio; Beebe, Kristin; Scroggins, Bradley; Neckers, Len; Altieri, Dario C. | ARTICLE | 847 |
2009-10 | Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones | Kang, Byoung Heon; Altieri, D. C. | ARTICLE | 862 |
2014-12 | Crystallization and preliminary X-ray diffraction analysis of Trap1 complexed with Hsp90 inhibitors | Kang, Byoung Heon; Jeong, Hanbin; Lee, Changwook | ARTICLE | 1176 |
2017-05-31 | Cyclophilin D defect impairs ROS regulation and increases invasion of cancer cells | Park,Hye-Kyung; Kang, Byoung Heon | CONFERENCE | 104 |
2015-02 | Cytotoxic effects of Tenebrio molitor larval extracts against hepatocellular carcinoma | Lee, ji-Eun; Lee, An-Jung; Jo, Da-Eun; Cho, Ju Hyeong; Youn, Kumju; Yun, Eun-Young; Hwang, Jae-Sam; Jun, Mira; Kang, Byoung Heon | ARTICLE | 1572 |
2021-07 | Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity | Yang, Sujae; Yoon, Nam Gu; Kim, Dongyoung; Park, Eunsun; Kim, So-Yeon; Lee, Ji Hoon; Lee, Changwook; Kang, Byoung Heon; Kang, Soosung | ARTICLE | 117 |
2015-04 | Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 | Lee, Changwook; Park, Hye-Kyung; Jeong, Hanbin; Lim, Jaehwa; Lee, An-Jung; Cheon, Keun Young; Kim, Chul-Su; Thomas, Ajesh P.; Bae, Boram; Kim, Nam Doo; Kim, Seong Heon; Suh, Pann-Ghill; Ryu, Ja-Hyoung; Kang, Byoung Heon | ARTICLE | 1252 |
2016-12-09 | Development of Hsp90 family protein inhibitors | Park, Hye-Kyung; Ko, Eunhwa; Lee, Geumwoo; Lee, Ji-Eun; Lee, Sang Kwang; Jeong, Hanbin; Lee, An-Jung; Im, Jin Young; Kim, Seong Heon; Lee, Changwook; Kang, Soosung; Kang, Byoung Heon | CONFERENCE | 162 |
2015-11-12 | Development of Hsp90 paralog specific inhibitors with mitochondrial drug delivery system | Kang, Byoung Heon | CONFERENCE | 97 |
2015-04-18 | Development of Hsp90 paralog specific inhibitors with mitochondrial drug delivery system | Kang, Byoung Heon | CONFERENCE | 1149 |