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CD13-targeting and TRAIL-displaying protein nanoparticles effectively induce apoptotic cell death of acute myeloid leukemia, prolonging survival in mouse models File

Jun, Heejin , Yeo, Mirae , Jeon, Jun Pyo , Eom, Soomin , Kim, Hyo Jeong , Kim, Yunjung , Jang, Eunjung , Park, Sung Ho , Kim, Eunhee , Kang, Sebyung

Article Issue Date2024-12 View309

Compact clustering of highly oligomerized anti-DR5 nanobodies effectively drives apoptotic cancer cell death, significantly suppressing tumor growth File

Kim, Yunjung , Mun, Jihyoung , Kim, Eojin , Roh, Hyungsuk , Eom, Soomin , Jun, Heejin , Kim, Hyo Jeong , Kim, Minseung , Jeon, Jun Pyo , Park, Sung Ho , et al

Article Issue Date2025-12 View13786

Developing Porous Protein Cage Nanoparticles as Cargo-Loadable and Ligand-Displayable Modular Delivery Nanoplatforms File

Eom, Soomin , Jun, Heejin , Kim, Eojin , Min, Duyoung , Kim, Hansol , Kang, Sebyung

Article Issue Date2024-10 View173

Developing Protein-based injectable hydrogels using PCNA and SpyCatcher for controlled cargo load and release

Eom, Soomin , Park, Seong Guk , Jun, Heejin , Kang, Sebyung

Conference Paper Issue Date2023-08-22 View77

Directing ricin-based immunotoxins with targeting affibodies and KDEL signal peptide to cancer cells effectively induces apoptosis and tumor suppression File File

Park, Seong Guk , Kim, Heeyeon , Jun, Heejin , Choi, Sun Young , Kim, Eunhee , Kang, Sebyung

Article Issue Date2022-08 View163

Dual-liganded protein nanoparticles displaying TRAILs and EGFR binding affibodies enhance therapeutic efficacy against EGFR overexpressing triple negative breast cancers

Jun, Heejin , Park, Seong Guk , Kang, Sebyung

Conference Paper Issue Date2023-08-22 View94

Effective in vivo delivery of diphtheria toxin using protein cage nanoparticles for targeted cancer therapy File

Eom, Soomin , Park, Seong Guk , Jun, Heejin , Kim, Yunjung , Lee, Hyun Bin , Kang, Sebyung

Article Issue Date2025-08 View83

EGFR Affibody and PEG functionalized protein nanoparticles: Sustaining targeting and macrophage evasion File

Jang, Seonhye , Jun, Heejin , Eom, Soomin , Zhao, Sheng , Murthy, Niren , Kang, Sebyung , Kim, Hansol

Article Issue Date2025-05 View162

HER2-Targeting and TRAIL-Presenting Protein Nanoparticles Induce a Concentration-Dependent Biphasic Response in HER2-Positive Breast Cancer Cells File

Jeong, Diane , Kim, Junsu , Kim, Yunjung , Jun, Heejin , Eom, Soomin , Kang, Sebyung

Article Issue Date2026-03 View29

In situ forming and self-crosslinkable protein hydrogels for localized cancer therapy and topical wound healing File

Eom, Soomin , Park, Seong Guk , Koo, Yonghoe , Noh, Yeongjin , Choi, Cholong , Kim, Yunjung , Jun, Heejin , Cha, Chaenyung , Joo, Jinmyoung , Kang, Sebyung

Article Issue Date2025-02 View147

Lactate oxidase/vSIRPα conjugates efficiently consume tumor-produced lactates and locally produce tumor-necrotic H2O2 to suppress tumor growth File

Kang, Yujin , Yeo, Mirae , Choi, Hyukjun , Jun, Heejin , Eom, Soomin , Park, Seong Guk , Yoon, Haejin , Kim, Eunhee , Kang, Sebyung

Article Issue Date2023-03 View243

Leukemia-Targeting NK cell Nanoengagers Effectively Promote Robust NK Activation and Potent Anti-Acute Myeloid Leukemia Response File File

Kim, Hyo Jeong , Jun, Heejin , Lee, Hyun Bin , Eom, Soomin , Kim, Junsu , Jeon, Jun Pyo , Park, Sung Ho , Kang, Sebyung

Article Issue Date2026-04 View2

Protein cage nanoparticle-based NK cell-engaging nanodrones (NKeNDs) effectively recruit NK cells to target tumor sites and suppress tumor growth File

Park, Seong Guk , Kim, Hyo Jeong , Lee, Hyun Bin , Eom, Soomin , Jun, Heejin , Jang, Yeongim , Park, Sung Ho , Kang, Sebyung

Article Issue Date2024-02 View168

Protein Nanoparticles Simultaneously Displaying TRAIL and EGFR-Binding Ligands Effectively Induce Apoptotic Cancer Cell Death and Overcome EGFR-TKI Resistance in Lung Cancer File

Kim, Yunjung , Kim, Jiwoo , Eom, Soomin , Jun, Heejin , Lee, Hyun Bin , Jeong, Diane , Kang, Sebyung

Article Issue Date2025-04 View108

Target-switchable Gd(III)-DOTA/protein cage nanoparticle conjugates with multiple targeting affibody molecules as target selective T1 contrast agents for high-field MRI File

Kim, Hansol , Jin, Seokha , Choi, Hyukjun , Kang, Mungsoo , Park SeongGuk , Jun, Heejin , Cho, Hyungjoon , Kang, Sebyung

Article Issue Date2021-07 View117

Targeted cancer therapy using protein nanoparticles dual-displaying TRAIL and cancer-targeting ligands File

Jun, Heejin

Thesis Issue Date2025-08 View64

Targeted Therapy for CD13-Overexpressing Triple-Negative Breast Cancers Using Apoptosis-Inducing Protein Cage Nanoparticles File File

Jun, Heejin , Kim, Junsu , Eom, Soomin , Jeong, Diane , Kang, Sebyung

Article Issue Date2026-02 View15

Targeting RBM39 with Tasisulam enhances TRAIL-induced apoptosis through DR5 upregulation and Bcl-2 downregulation in renal cell carcinoma File

Jang, Ji Hoon , Kim, Haein , Jun, Heejin , Park, Cho-Young , Kim, Joo-Young , Shin, Yerim , Yeo, Mirae , Kim, Hunmin , Kang, Sebyung , Kim, Eunhee , et al

Article Issue Date2025-06 View215

TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth File

Jun, Heejin , Jang, Eunjung , Kim, Hansol , Yeo, Mirae , Park, Seong Guk , Lee, Jaehyeok , Shin, Kyeong Jin , Chae, Young Chan , Kang, Sebyung , Kim, Eunhee

Article Issue Date2022-09 View234

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