In addition to the great impact on the progress of quantum mechanics at its early stage, Stern-Gerlachexperiment, the study on interaction of atoms with magnetic field, has lead to the invention of nuclear magnetic resonance and magnetic resonance imaging. As this classical example, the investigation of particle-field interaction has been beneficial to whole science area. Main topic of our group is experimental research and application of molecular interaction with various fields, such as nonresonant laser field and its combination with static electric field. The force imparted by the molecule-field interaction is exploited to spatially separate stereoisomers and their quantum states. Beside, in collaboration with Fritz Haber Institute in Berlin, grazing incidence atom optics is investigated.