Full metadata record
DC Field | Value | Language |
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dc.citation.endPage | 284 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 271 | - |
dc.citation.title | EXPERIMENTAL NEUROBIOLOGY | - |
dc.citation.volume | 32 | - |
dc.contributor.author | Chae, Soyoung | - |
dc.contributor.author | Sihn, Duho | - |
dc.contributor.author | Kim, Sung-Phil | - |
dc.date.accessioned | 2024-01-03T17:05:10Z | - |
dc.date.available | 2024-01-03T17:05:10Z | - |
dc.date.created | 2024-01-03 | - |
dc.date.issued | 2023-08 | - |
dc.description.abstract | Decision-making is a complex process that involves the integration and interpretation of sensory information to guide actions. The rodent motor cortex, which is generally involved in motor planning and execution, also plays a critical role in decision-making processes. In perceptual delayedresponse tasks, the rodent motor cortex can represent sensory cues, as well as the decision of where to move. However, it remains unclear whether erroneous decisions arise from incorrect encoding of sensory information or improper utilization of the collected sensory information in the motor cortex. In this study, we analyzed the rodent anterior lateral motor cortex (ALM) while the mice performed perceptual delayed-response tasks. We divided population activities into sensory and choice signals to separately examine the encoding and utilization of sensory information. We found that the encoding of sensory information in the error trials was similar to that in the hit trials, whereas choice signals evolved differently between the error and hit trials. In error trials, choice signals displayed an offset in the opposite direction of instructed licking even before stimulus presentation, and this tendency gradually increased after stimulus onset, leading to incorrect licking. These findings suggest that decision errors are caused by biases in choice-related activities rather than by incorrect sensory encoding. Our study elaborates on the understanding of decisionmaking processes by providing neural substrates for erroneous decisions. | - |
dc.identifier.bibliographicCitation | EXPERIMENTAL NEUROBIOLOGY, v.32, no.4, pp.271 - 284 | - |
dc.identifier.doi | 10.5607/en23020 | - |
dc.identifier.issn | 1226-2560 | - |
dc.identifier.scopusid | 2-s2.0-85174914784 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/67599 | - |
dc.identifier.wosid | 001100847100005 | - |
dc.language | 영어 | - |
dc.publisher | KOREAN SOC BRAIN & NEURAL SCIENCE, KOREAN SOC NEURODEGENERATIVE DISEASE | - |
dc.title | Bias in Prestimulus Motor Cortical Activity Determines Decision-making Error in Rodents | - |
dc.type | Article | - |
dc.description.isOpenAccess | TRUE | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental; Neurosciences | - |
dc.relation.journalResearchArea | Research & Experimental Medicine; Neurosciences & Neurology | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Decision making | - |
dc.subject.keywordAuthor | Motor cortex | - |
dc.subject.keywordAuthor | Mice | - |
dc.subject.keywordPlus | CORTEX | - |
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