Nickel-Iron Hydrogenases: High-Resolution Crystallography Resolves the Hydride, but Not the Debate
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- Nickel-Iron Hydrogenases: High-Resolution Crystallography Resolves the Hydride, but Not the Debate
- Schilter, David
- Issue Date
- WILEY-V C H VERLAG GMBH
- CHEMBIOCHEM, v.16, no.12, pp.1712 - 1714
- An (X-ray) eye for detail: Modern high-resolution protein crystallography allows H atoms to be located. Applied to nickel–iron hydrogenase, X-ray structural analysis has finally confirmed the presence of an active-site hydride and thiol, as well as unveiling the intricate pathways that protons take to and from the active site.
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