File Download

There are no files associated with this item.

  • Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
Related Researcher

김성진

Kim, Seong-Jin
Bio-inspired Advanced Sensors Lab.
Read More

Views & Downloads

Detailed Information

Cited time in webofscience Cited time in scopus
Metadata Downloads

Real-time label-free quantitative monitoring of biomolecules without surface binding by floating-gate complementary metal-oxide semiconductor sensor array integrated with readout circuitry

Author(s)
Kim, Seong-JinYoo, KyutaeShim, JeoyoungChung, WonseokKo, ChristopherIm, MaesoonKim, Lee-SupYoon, Euisik
Issued Date
2007-11
DOI
10.1063/1.2803848
URI
https://scholarworks.unist.ac.kr/handle/201301/12383
Fulltext
http://scitation.aip.org/content/aip/journal/apl/91/20/10.1063/1.2803848
Citation
APPLIED PHYSICS LETTERS, v.91, pp.203903
Abstract
We report a label-free field-effect sensing array integrated with complementary metal-oxide semiconductor (CMOS) readout circuitry to detect the surface potential determined by the negative charge in DNA molecules. For real-time DNA quantification, we have demonstrated the measurements of DNA molecules without immobilizing them on the sensing surface which is composed of an array of floating-gate CMOS transistors. This nonimmobilizing technique allows the continuous monitoring of the amount of charged molecules by injecting DNA solutions sequentially. We have carried out the real-time quantitative measurement of 19 bp oligonucleotides and analyzed its sensitivity as a function of pH in buffer solutions. (c) 2007 American Institute of Physics.
Publisher
AMER INST PHYSICS
ISSN
0003-6951

qrcode

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.