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고명곤
Ko, Myunggon

고명곤

Department of Biological Sciences(생명과학과)

Research Interests
Leukemia;hematopoiesis;obesity;diabetes;metabolic disease;cancer therapy;cancer
Lab Description
How do alterations in epigenetic landscape disturb the barrier between normal and malignant states to cause cancers? How can we translate these cancer-related aberrations into more efficient cancer therapy? These are two overarching questions that our research is currently addressing. The intricate interplay between genetic and epigenetic pathways plays key roles in regulating normal and malignant cellular development.
Researcher ID Research Gate ORCiD Scopus Google Scholar
Previous
Ultrasensitive detection of 5-hydroxymethylcytosine in genomic DNA using a graphene-based sensor modified with biotin and gold nanoparticles File File

Imran, Habibulla , Lee, Hyun-ji , Alam, Asrar , An, Jungeun , Ko, Myunggon , Lim, Sooman

Article Issue Date2024-08 View26
TET Enzymes in the Immune System: From DNA Demethylation to Immunotherapy, Inflammation, and Cancer File

Lopez-Moyado, Isaac.F. , Ko, Myunggon , Hogan, Patrick , Rao, Anjana

Article Issue Date2024-02 View23
Development of Novel Epigenetic Anti-Cancer Therapy Targeting TET Proteins File File

Kim, Hyejin , Jung, Inkyung , Lee, Chan Hyeong , An, Jungeun , Ko, Myunggon

Article Issue Date2023-11 View19
Editorial for the Special Issue “Molecular Mechanism of Leukemia” File

An, Jungeun , Ko, Myunggon

Article Issue Date2023-09 View9
Pharmacological GLUT3 salvage augments the efficacy of vitamin C-induced TET2 restoration in acute myeloid leukemia File

Liu, Jun , Min, Suji , Kim, Dongchan , Park, Eunchae , Pei, Shanshan , Koh, Youngil , Shin, Dong-Yeop , Byun, Ja Min , Ko, Myunggon , Yoon, Sung-Soo , et al

Article Issue Date2023-08 View21
Highly selective and real-time detection of 5-hydroxymethylcytosine in genomic DNA using a carbon nitride-modified gold transducer-based electrochemical sensor File

Imran, Habibulla , An, Jungeun , Jang, Kyumin , Alam, Aslar , Dharuman, Venkataraman , Ko, Myunggon , Lim, Sooman

Article Issue Date2023-03 View22
Epigenetic Regulators of DNA Cytosine Modification: Promising Targets for Cancer Therapy File File

Jung, Inkyung , An, Jungeun , Ko, Myunggon

Article Issue Date2023-02 View16
Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch File

Yuita, Hiroshi , Lopez-Moyado, Isaac , Jeong, Hyeongmin , Chen, Arthur Xiuyang , Scott-Browne, James , An, Jungeun , Nakayama, Toshinori , Onodera, Atsushi , Ko, Myunggon , Rao, Anjana

Article Issue Date2023-02 View16
Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation File File

Ko, Myunggon , An, Jungeun

Article Issue Date2023-01 View16
BAP1 shapes the bone marrow niche for lymphopoiesis by fine-tuning epigenetic profiles in endosteal mesenchymal stromal cells File

Jeong, Jinguk , Jung, Inkyung , Kim, Ji-Hoon , Jeon, Shin , Hyeon, Do Young , Min, Hyungyu , Kang, Byeonggeun , Nah, Jinwoo , Hwang, Daehee , Um, Soo-Jong , et al

Article Issue Date2022-11 View15
A fast and label-free detection of hydroxymethylated DNA using a nozzle-jet printed AuNPs@Ti3C2 MXene-based electrochemical sensor File

Bhat, Kiesar Sideeq , Byun, Seongjun , Alam, Asrar , Ko, Myunggon , An, Jungeun , Lim, Sooman

Article Issue Date2022-07 View21
Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression File File

Byun, Seongjun , Lee, Chan Hyeong , Jeong, Hyumgmin , Kim, Hyejin , Kwon, Hyug Moo , Park, Sung Ho , Myung, Kyungjae , An, Jungeun , Ko, Myunggon

Article Issue Date2022-06 View25
Rapid and Label-Free Detection of 5-Hydroxymethylcytosine in Genomic DNA Using an Au/ZnO Nanorods Hybrid Nanostructure-Based Electrochemical Sensor File

Bhat, Kiesar Sideeq , Kim, Hyejin , Alam, Asrar , Ko, Myunggon , An, Jungeun , Lim, Sooman

Article Issue Date2021-11 View21
Direct and rapid detection of 5-hydroxymethylcytosine, a novel cancer hallmark in DNA, using electrochemical reaction File

Lee, Seo Yeon , Qi, Xu , Ko, Myunggon , Park, Chan Hee , An, Jungeun , Lim, Sooman

Article Issue Date2020-12 View20
Decoding ribosomes to keep growing (in AML) File

An, Jungeun , Ko, Myunggon

Article Issue Date2020-06 View16
Decreased vitamin C uptake mediated by SLC2A3 promotes leukaemia progression and impedes TET2 restoration File

Liu, Jun , Hong, Junshik , Han, Heejoo , Park, Jihyun , Kim, Dongchan , Park, Hyejoo , Ko, Myunggon , Koh, Youngil , Shin, Dong-Yeop , Yoon, Sung-Soo

Article Issue Date2020-05 View9
TET family dioxygenases and DNA demethylation in stem cells and cancers File File

An, Jungeun , Rao, Anjana , Ko, Myunggon

Article Issue Date2017-04 View17
DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases File File

Nair, Varun Sasidharan , Song, Mi Hye , Ko, Myunggon , Oh, Kwon Ik

Article Issue Date2016-12 View17
DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells File

Zhang, Xiaotian , Su, Jianzhong , Jeong, Mira , Ko, Myunggon , Huang, Yun , Park, Hyun Jung , Guzman, Anna , Lei, Yong , Huang, Yung-Hsin , Rao, Anjana , et al

Article Issue Date2016-09 View12
TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities File File

Montagner, Sara , Leoni, Cristina , Emming, Stefan , Chiara, Della Giulia , Balestrieri, Chiara , Barozzi, Iros , Piccolo Viviana , Togher, Susan , Ko, Myunggon , Rao, Anjana , et al

Article Issue Date2016-05 View12
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