사진

  • Scopus

Park, Tae-Eun (박태은)

Department
Department of Biomedical Engineering(바이오메디컬공학과)
Website
http://www.mtenlab.com
Lab
Micro Tissue Engineering & Nanomedicine Lab. (미세조직공학 및 나노의학 연구실)
Research Keywords
오간온어칩, 오가노이드, 바이오칩, 나노의학, 파지디스플레이, Organ-on-a-Chip, Organoid, BioChip, Nanotherapeutic, Phage Display
Research Interests
Human body is the most complex organic system in nature. To understand its integrated physiological functions, it is important to recapitulate multi-cellular interactions in tissue and map networks of dynamical organ system in vitro. An ‘Organ on a chip’ is microfluidic cell culture device that contains microenvironment of living organ, which could revolutionize drug development as alternatives to animal testing. We are developing ‘organ-on-a-chip’ using multiple cell types or organoid system to emulate human organs in different physiological states. For precision medicine, we are also creating personalized organ model using stem cell source. Through human in vivo-like organ model, we develop new approach to screen drug and targeted drug delivery, and test drug and observe reactions in real time. Finally, we aim to develop safe and efficient nanomedicines which target specific physiological microenvironment.
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2023-073D microengineered vascularized tumor spheroids for drug delivery and efficacy testingAhn, Jungho; Kim, Da-Hyun; Koo, Dong-Jun, et alARTICLE985 3D microengineered vascularized tumor spheroids for drug delivery and efficacy testing
2023-07Organoid‐Based Human Stomach Micro‐Physiological System to Recapitulate the Dynamic Mucosal Defense MechanismJeong, Hye‐Jin; Park, Ji‐Hyeon; Kang, Joo H., et alARTICLE194 Organoid‐Based Human Stomach Micro‐Physiological System to Recapitulate the Dynamic Mucosal Defense Mechanism
2023-06Intestinal Peyer's Patches: Structure, Function, and In Vitro ModelingPark, Jung In; Cho, Seung Woo; Kang, Joo H., et alARTICLE852 Intestinal Peyer's Patches: Structure, Function, and In Vitro Modeling
2023-06Nematic Fibrin Fibers Enabling Vascularized Thrombus Implants Facilitate Scarless Cutaneous Wound HealingJung, Su Hyun; Jang, Bong Hwan; Kwon, Seyong, et alARTICLE568 Nematic Fibrin Fibers Enabling Vascularized Thrombus Implants Facilitate Scarless Cutaneous Wound Healing
2023-06Facile and adhesive-free method for bonding nanofiber membrane onto thermoplastic polystyrene substrate to fabricate 3D cell culture platformsYoun, Jaeseung; Rhyou, Junyeol; Kim, Dohui, et alARTICLE638 Facile and adhesive-free method for bonding nanofiber membrane onto thermoplastic polystyrene substrate to fabricate 3D cell culture platforms
2023-05Aptamer Nanoconstructs Crossing Human Blood–Brain Barrier Discovered via Microphysiological System-Based SELEX TechnologyChoi, Jeong-Won; Seo, Minwook; Kim, Kyunghwan, et alARTICLE848 Aptamer Nanoconstructs Crossing Human Blood–Brain Barrier Discovered via Microphysiological System-Based SELEX Technology
2023-03Integrated technologies for continuous monitoring of organs-on-chips: Current challenges and potential solutionsSabaté del Río, Jonathan; Ro, Jooyoung; Yoon, Heejeong, et alARTICLE1233 Integrated technologies for continuous monitoring of organs-on-chips: Current challenges and potential solutions
2023-03Microphysiological system recapitulating the pathophysiology of adipose tissue in obesityYoon, Heejeong; Seo, Jeong Kon; Park, Tae-EunARTICLE741 Microphysiological system recapitulating the pathophysiology of adipose tissue in obesity
2023-02Human iPS-derived blood-brain barrier model exhibiting enhanced barrier properties empowered by engineered basement membraneChoi, Jeong-Won; Youn, Jaeseung; Kim, Dong Sung, et alARTICLE1141 Human iPS-derived blood-brain barrier model exhibiting enhanced barrier properties empowered by engineered basement membrane
2022-10Image-guided in situ cancer vaccination with combination of multi-functional nano-adjuvant and an irreversible electroporation techniqueHan, Jun-Hyeok; Lee, Yun Young; Shin, Ha Eun, et alARTICLE789 Image-guided in situ cancer vaccination with combination of multi-functional nano-adjuvant and an irreversible electroporation technique
2022-04Essential cues of engineered polymeric materials regulating gene transfer pathwaysAriful Islam, Mohammad; Park, Tae-Eun; Firdous, Jannatul, et alARTICLE657 Essential cues of engineered polymeric materials regulating gene transfer pathways
2022-01A novel therapeutic strategy of multimodal nanoconjugates for state-of-the-art brain tumor phototherapyKim, Hyung Shik; Seo, Minwook; Park, Tae-Eun, et alARTICLE496 A novel therapeutic strategy of multimodal nanoconjugates for state-of-the-art brain tumor phototherapy
2021-10Condensed ECM-based nanofilms on highly permeable PET membranes for robust cell-to-cell communications with improved optical clarityChoi, Brian; Choi, Jeong-Won; Jin, Hyungwon, et alARTICLE731 Condensed ECM-based nanofilms on highly permeable PET membranes for robust cell-to-cell communications with improved optical clarity
2021-08Recent advances with liposomes as drug carriers for treatment of neurodegenerative diseasesSeo, Min-Wook; Park, Tae-EunARTICLE354 Recent advances with liposomes as drug carriers for treatment of neurodegenerative diseases
2021-02Biofouling-resistant tubular fluidic devices with magneto-responsive dynamic wallsChoi, Geonjun; Ko, Hangil; Jang, Hyejin, et alARTICLE544 Biofouling-resistant tubular fluidic devices with magneto-responsive dynamic walls
2020-12Engineering Human Brain Organoids: From Basic Research to Tissue RegenerationJeong, Hye-Jin; Jimenez, Zuly; Mukhambetiyar, Karakoz, et alARTICLE757 Engineering Human Brain Organoids: From Basic Research to Tissue Regeneration
2020-12LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradientLee, Jongbo; Park, Jumin; Kim, Ji-hyung, et alARTICLE705 LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient
2020-04Robotic fluidic coupling and interrogation of multiple vascularized organ chipsNovak, Richard; Ingram, Miles; Marquez, Susan, et alARTICLE916 Robotic fluidic coupling and interrogation of multiple vascularized organ chips
2020-02PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273Khim, Keon Woo; Choi, Sun Sil; Jang, Hyun-Jun, et alARTICLE796 PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273
2019-12Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via TranscytosisMorad, Golnaz; Carman, Christopher V.; Hagedorn, Elliott J., et alARTICLE789 Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via Transcytosis

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