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Park, Tae-Eun (박태은)

Department
Department of Biomedical Engineering(바이오메디컬공학과)
Website
http://www.mtenlab.com
Lab
Micro Tissue Engineering & Nanomedicine Lab. (미세조직공학 및 나노의학 연구실)
Research Keywords
오간온어칩, 오가노이드, 바이오칩, 나노의학, 파지디스플레이, Organ-on-a-Chip, Organoid, BioChip, Nanotherapeutic, Phage Display
Research Interests
Human body is the most complex organic system in nature. To understand its integrated physiological functions, it is important to recapitulate multi-cellular interactions in tissue and map networks of dynamical organ system in vitro. An ‘Organ on a chip’ is microfluidic cell culture device that contains microenvironment of living organ, which could revolutionize drug development as alternatives to animal testing. We are developing ‘organ-on-a-chip’ using multiple cell types or organoid system to emulate human organs in different physiological states. For precision medicine, we are also creating personalized organ model using stem cell source. Through human in vivo-like organ model, we develop new approach to screen drug and targeted drug delivery, and test drug and observe reactions in real time. Finally, we aim to develop safe and efficient nanomedicines which target specific physiological microenvironment.
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2021-02Biofouling-resistant tubular fluidic devices with magneto-responsive dynamic wallsChoi, Geonjun; Ko, Hangil; Jang, Hyejin, et alARTICLE28 Biofouling-resistant tubular fluidic devices with magneto-responsive dynamic walls
2020-12Engineering Human Brain Organoids: From Basic Research to Tissue RegenerationJeong, Hye-Jin; Jimenez, Zuly; Mukhambetiyar, Karakoz, et alARTICLE148 Engineering Human Brain Organoids: From Basic Research to Tissue Regeneration
2020-12LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradientLee, Jongbo; Park, Jumin; Kim, Ji-hyung, et alARTICLE120 LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient
2020-04Robotic fluidic coupling and interrogation of multiple vascularized organ chipsNovak, Richard; Ingram, Miles; Marquez, Susan, et alARTICLE210 Robotic fluidic coupling and interrogation of multiple vascularized organ chips
2020-02PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273Khim, Keon Woo; Choi, Sun Sil; Jang, Hyun-Jun, et alARTICLE252 PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273
2019-12Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via TranscytosisMorad, Golnaz; Carman, Christopher V.; Hagedorn, Elliott J., et alARTICLE258 Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via Transcytosis
2019-11Robust chemical bonding of PMMA microfluidic devices to porous PETE membranes for reliable cytotoxicity testing of drugsNgyuen, Thao; Jung, Su Hyun; Lee, Min Seok, et alARTICLE311 Robust chemical bonding of PMMA microfluidic devices to porous PETE membranes for reliable cytotoxicity testing of drugs
2019-10Hydrogel Nanospike Patch as a Flexible Anti-Pathogenic Scaffold for Regulating Stem Cell BehaviorPark, Sunho; Park, Hyun-Ha; Sun, Kahyun, et alARTICLE271 Hydrogel Nanospike Patch as a Flexible Anti-Pathogenic Scaffold for Regulating Stem Cell Behavior
2019-073D Microfluidic Bone Tumor Microenvironment Comprised of Hydroxyapatite/Fibrin CompositeAhn, Jungho; Lim, Jungeun; Jusoh, Norhana, et alARTICLE282 3D Microfluidic Bone Tumor Microenvironment Comprised of Hydroxyapatite/Fibrin Composite
2019-06Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodiesPark, Tae-Eun; Mustafaoglu, Nur; Herland, Anna, et alARTICLE399 Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
2018-09A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cellsMaoz, Ben N; Herland, Anna; FitzGerald, Edward A, et alARTICLE451 A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells
2018-08Investigation on vascular cytotoxicity and extravascular transport of cationic polymer nanoparticles using perfusable 3D microvessel modelAhn, Jungho; Cho, Chong-Su; Cho, Seong Woo, et alARTICLE679 Investigation on vascular cytotoxicity and extravascular transport of cationic polymer nanoparticles using perfusable 3D microvessel model
2016-09A high affinity kidney targeting by chitobionic acid-conjugated polysorbitol gene transporter alleviates unilateral ureteral obstruction in ratsIslam, Mohammad Ariful; Kim, Sanghwa; Firdous, Jannatul, et alARTICLE416 A high affinity kidney targeting by chitobionic acid-conjugated polysorbitol gene transporter alleviates unilateral ureteral obstruction in rats
2016-07Nasal immunization with mannan-decorated mucoadhesive HPMCP microspheres containing ApxIIA toxin induces protective immunity against challenge infection with Actinobacillus pleuropneumoiae in miceLi, Hui-Shan; Shin, Min-Kyoung; Singh, Bijay, et alARTICLE484 Nasal immunization with mannan-decorated mucoadhesive HPMCP microspheres containing ApxIIA toxin induces protective immunity against challenge infection with Actinobacillus pleuropneumoiae in mice
2016-04Gene therapy for bone tissue engineeringKim, Young-Dong; Pofali, Prasad; Park, Tae-Eun, et alARTICLE450 Gene therapy for bone tissue engineering
2016-03Influence of Flaxseed Oil on Fecal Microbiota, Egg Quality and Fatty Acid Composition of Egg Yolks in Laying HensLee, Jun-Yeong; Kang, Sang-Kee; Heo, Yun-Jeong, et alARTICLE450 Influence of Flaxseed Oil on Fecal Microbiota, Egg Quality and Fatty Acid Composition of Egg Yolks in Laying Hens
2016-03Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a ChipHerland, Anna; van der Meer, Andries D.; FitzGerald, Edward A., et alARTICLE423 Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip
2016-03Efficient gene transfection to liver cells via the cellular regulation of a multifunctional polylactitol-based gene transporterKim, Young-Dong; Park, Tae-Eun; Singh, Bijay, et alARTICLE441 Efficient gene transfection to liver cells via the cellular regulation of a multifunctional polylactitol-based gene transporter
2015-12Mannan-decorated thiolated Eudragit microspheres for targeting antigen presenting cells via nasal vaccinationLi, Hui-Shan; Singh, Bijay; Park, Tae-Eun, et alARTICLE366 Mannan-decorated thiolated Eudragit microspheres for targeting antigen presenting cells via nasal vaccination
2015-11Image-guided nanoparticle-based siRNA delivery for cancer therapyKim, Yong-Dong; Park, Tae-Eun; Singh, Bijay, et alARTICLE368 Image-guided nanoparticle-based siRNA delivery for cancer therapy

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