사진

  • Scopus

Park, Tae-Eun (박태은)

Department
Department of Biomedical Engineering(바이오메디컬공학과)
Website
http://www.mtenlab.com
Lab
Micro Tissue Engineering & Nanomedicine Lab. (미세조직공학 및 나노의학 연구실)
Research Keywords
오간온어칩, 오가노이드, 바이오칩, 나노의학, 파지디스플레이, Organ-on-a-Chip, Organoid, BioChip, Nanotherapeutic, Phage Display
Research Interests
Human body is the most complex organic system in nature. To understand its integrated physiological functions, it is important to recapitulate multi-cellular interactions in tissue and map networks of dynamical organ system in vitro. An ‘Organ on a chip’ is microfluidic cell culture device that contains microenvironment of living organ, which could revolutionize drug development as alternatives to animal testing. We are developing ‘organ-on-a-chip’ using multiple cell types or organoid system to emulate human organs in different physiological states. For precision medicine, we are also creating personalized organ model using stem cell source. Through human in vivo-like organ model, we develop new approach to screen drug and targeted drug delivery, and test drug and observe reactions in real time. Finally, we aim to develop safe and efficient nanomedicines which target specific physiological microenvironment.
This table browses all dspace content
Issue DateTitleAuthor(s)TypeViewAltmetrics
2020-04Engineering Human Brain Organoids: From Basic Research to Tissue RegenerationJeong, Hye-Jin; Jimenez, Zuly; Mukhambetiyar, Karakoz, et alARTICLE67 Engineering Human Brain Organoids: From Basic Research to Tissue Regeneration
2020-02PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273Khim, Keon Woo; Choi, Sun Sil; Jang, Hyun-Jun, et alARTICLE187 PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273
2020-01Robotic fluidic coupling and interrogation of multiple vascularized organ chipsNovak, Richard; Ingram, Miles; Marquez, Susan, et alARTICLE116 Robotic fluidic coupling and interrogation of multiple vascularized organ chips
2019-12Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via TranscytosisMorad, Golnaz; Carman, Christopher V.; Hagedorn, Elliott J., et alARTICLE195 Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via Transcytosis
2019-11Robust chemical bonding of PMMA microfluidic devices to porous PETE membranes for reliable cytotoxicity testing of drugsNgyuen, Thao; Jung, Su Hyun; Lee, Min Seok, et alARTICLE245 Robust chemical bonding of PMMA microfluidic devices to porous PETE membranes for reliable cytotoxicity testing of drugs
2019-10Hydrogel Nanospike Patch as a Flexible Anti-Pathogenic Scaffold for Regulating Stem Cell BehaviorPark, Sunho; Park, Hyun-Ha; Sun, Kahyun, et alARTICLE212 Hydrogel Nanospike Patch as a Flexible Anti-Pathogenic Scaffold for Regulating Stem Cell Behavior
2019-073D Microfluidic Bone Tumor Microenvironment Comprised of Hydroxyapatite/Fibrin CompositeAhn, Jungho; Lim, Jungeun; Jusoh, Norhana, et alARTICLE221 3D Microfluidic Bone Tumor Microenvironment Comprised of Hydroxyapatite/Fibrin Composite
2019-06Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodiesPark, Tae-Eun; Mustafaoglu, Nur; Herland, Anna, et alARTICLE330 Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
2018-09A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cellsMaoz, Ben N; Herland, Anna; FitzGerald, Edward A, et alARTICLE403 A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells
2018-08Investigation on vascular cytotoxicity and extravascular transport of cationic polymer nanoparticles using perfusable 3D microvessel modelAhn, Jungho; Cho, Chong-Su; Cho, Seong Woo, et alARTICLE606 Investigation on vascular cytotoxicity and extravascular transport of cationic polymer nanoparticles using perfusable 3D microvessel model
2016-09A high affinity kidney targeting by chitobionic acid-conjugated polysorbitol gene transporter alleviates unilateral ureteral obstruction in ratsIslam, Mohammad Ariful; Kim, Sanghwa; Firdous, Jannatul, et alARTICLE378 A high affinity kidney targeting by chitobionic acid-conjugated polysorbitol gene transporter alleviates unilateral ureteral obstruction in rats
2016-07Nasal immunization with mannan-decorated mucoadhesive HPMCP microspheres containing ApxIIA toxin induces protective immunity against challenge infection with Actinobacillus pleuropneumoiae in miceLi, Hui-Shan; Shin, Min-Kyoung; Singh, Bijay, et alARTICLE441 Nasal immunization with mannan-decorated mucoadhesive HPMCP microspheres containing ApxIIA toxin induces protective immunity against challenge infection with Actinobacillus pleuropneumoiae in mice
2016-04Gene therapy for bone tissue engineeringKim, Young-Dong; Pofali, Prasad; Park, Tae-Eun, et alARTICLE396 Gene therapy for bone tissue engineering
2016-03Influence of Flaxseed Oil on Fecal Microbiota, Egg Quality and Fatty Acid Composition of Egg Yolks in Laying HensLee, Jun-Yeong; Kang, Sang-Kee; Heo, Yun-Jeong, et alARTICLE407 Influence of Flaxseed Oil on Fecal Microbiota, Egg Quality and Fatty Acid Composition of Egg Yolks in Laying Hens
2016-03Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a ChipHerland, Anna; van der Meer, Andries D.; FitzGerald, Edward A., et alARTICLE373 Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip
2016-03Efficient gene transfection to liver cells via the cellular regulation of a multifunctional polylactitol-based gene transporterKim, Young-Dong; Park, Tae-Eun; Singh, Bijay, et alARTICLE384 Efficient gene transfection to liver cells via the cellular regulation of a multifunctional polylactitol-based gene transporter
2015-12Mannan-decorated thiolated Eudragit microspheres for targeting antigen presenting cells via nasal vaccinationLi, Hui-Shan; Singh, Bijay; Park, Tae-Eun, et alARTICLE327 Mannan-decorated thiolated Eudragit microspheres for targeting antigen presenting cells via nasal vaccination
2015-11Image-guided nanoparticle-based siRNA delivery for cancer therapyKim, Yong-Dong; Park, Tae-Eun; Singh, Bijay, et alARTICLE321 Image-guided nanoparticle-based siRNA delivery for cancer therapy
2015-11Soluble RANKL expression in Lactococcus lactis and investigation of its potential as an oral vaccine adjuvantKim, Jeong-In; Park, Tae-Eun; Maharjan, Sushila, et alARTICLE333 Soluble RANKL expression in Lactococcus lactis and investigation of its potential as an oral vaccine adjuvant
2015-09Mucoadhesive Chitosan Derivatives as Novel Drug CarriersIslam, Mohammad Ariful; Park, Tae-Eun; Reesor, Emma, et alARTICLE381 Mucoadhesive Chitosan Derivatives as Novel Drug Carriers

MENU