사진

Chae, Young Chan (채영찬)

Department
Department of Biological Sciences(생명과학과)
Lab
Cancer Translational Research Lab. (암 중개 연구실)
Research Keywords
Cancer Metabolism, Stress Response of Cancer, Mitochondria of Cancer, Tumor Microenvironment
Research Interests
Research interest in Cancer Metabolism, Stress Response of Cancer, Mitochondria of Cancer, Molecular Mechanisms of Cancer Initiation, Progression and Therapy, Mechanism of tumor therapeutic resistance.
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2021-04Accessibility-dependent topology studies of membrane proteins using a SpyTag/SpyCatcher protein-ligation systemBae, Yoonji; Lee, Sang Kwon; Chae, Young Chan, et alARTICLE23 Accessibility-dependent topology studies of membrane proteins using a SpyTag/SpyCatcher protein-ligation system
2021-02LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survivalLee, Yu Geon; Kim, Hui Won; Nam, Yeji, et alARTICLE71 LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival
2020-09Selective and Effective Cancer Treatments using Target‐Switchable Intracellular Bacterial Toxin Delivery SystemsPark, Seong Guk; Choi, Bongseo; Bae, Yoonji, et alARTICLE132 Selective and Effective Cancer Treatments using Target‐Switchable Intracellular Bacterial Toxin Delivery Systems
2020-09GDC-0980 (apitolisib) treatment with gemcitabine and/or cisplatin synergistically reduces cholangiocarcinoma cell growth by suppressing the PI3K/Akt/mTOR pathwayJang, Dong Kee; Lee, Yu Geon; Chae, Young Chan, et alARTICLE64 GDC-0980 (apitolisib) treatment with gemcitabine and/or cisplatin synergistically reduces cholangiocarcinoma cell growth by suppressing the PI3K/Akt/mTOR pathway
2020-06Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasisChoi, Sun Sil; Lee, Sang Kwon; Kim, Joong Kwan, et alARTICLE272 Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis
2020-02Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancerLee, Yu Geon; Nam, Yeji; Shin, Kyeong Jin, et alARTICLE305 Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer
2020-01Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCerJang, Hyun-Jun; Lim, Seyoung; Kim, Jung-Min, et alARTICLE324 Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer
2020-01ITGB4-mediated metabolic reprogramming of cancer-associated fibroblastsSung, Jin Sol; Kang, Chan Woo; Kang, Suki, et alARTICLE296 ITGB4-mediated metabolic reprogramming of cancer-associated fibroblasts
2020-01Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1Park, Hye-Kyung; Yoon, Nam Gu; Lee, Ji-Eun, et alARTICLE237 Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1
2019-12MFF REGULATION OF MITOCHONDRIAL CELL DEATH IS A THERAPEUTIC TARGET IN CANCERSeo, Jae Ho; Chae, Young Chan; Kossenkov, Andrew V, et alARTICLE273 MFF REGULATION OF MITOCHONDRIAL CELL DEATH IS A THERAPEUTIC TARGET IN CANCER
2019-10Phospholipase C-β1 potentiates glucose-stimulated insulin secretionHwang, Hyeon-Jeong; Yang, Yong Ryoul; Kim, Hye Yun, et alARTICLE397 Phospholipase C-β1 potentiates glucose-stimulated insulin secretion
2019-10Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancerSeo, Jae Ho; Agarwal, Ekta; Chae, Young Chan, et alARTICLE257 Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer
2019-04Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cellsPark, Hye-Kyung; Hong, Jun-Hee; Oh, Young Taek, et alARTICLE386 Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells
2018-07Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial HypertensionBoucherat, Olivier; Peterlini, Thibaut; Bourgeois, Alice, et alARTICLE567 Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension
2018-07Cancer stem cell metabolism: target for cancer therapyChae, Young Chan; Kim, Jae HoARTICLE498 Cancer stem cell metabolism: target for cancer therapy
2018-03Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formationKim, Da Yeon; Jung, Seok Yun; Kim, Yeon Ju, et alARTICLE516 Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formation
2018-01PLCγ1: Potential arbitrator of cancer progressionJang, Hyun-Jun; Suh, Pann-Ghill; Lee, Yu Jin, et alARTICLE686 PLCγ1: Potential arbitrator of cancer progression
2017-12A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapyBryant, Kelly G.; Chae, Young Chan; Martinez, Rogelio L., et alARTICLE504 A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy
2016-08Mitochondrial Akt Regulation of Hypoxic Tumor ReprogrammingChae, Young Chan; Vaira, Valentina; Caino, M. Cecilia, et alARTICLE606 Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
2016-07The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and MetastasisSeo, Jae Ho; Rivadeneira, Dayana B.; Caino, M. Cecilia, et alARTICLE593 The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis

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