사진

Chae, Young Chan (채영찬)

Department
School of Life Sciences(생명과학부)
Research Interests
Cancer Metabolism, Stress Response of Cancer, Mitochondria of Cancer, Molecular Mechanisms of Cancer Initiation, Progression and Therapy, Autophagy in Cell Survival and Cancer Progression, Mechanism of tumor therapeutic resistance
Lab
Website
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2020-02Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancerLee, Yu Geon; Nam, Yeji; Shin, Kyeong Jin, et alARTICLE56 Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer
2020-01Glucosylceramide synthase regulates adipo-osteogenic differentiation through synergistic activation of PPARγ with GlcCerJang, Hyun-Jun; Lim, Seyoung; Kim, Jung-Min, et alARTICLE105 Glucosylceramide synthase regulates adipo-osteogenic differentiation through synergistic activation of PPARγ with GlcCer
2020-01ITGB4-mediated metabolic reprogramming of cancer-associated fibroblastsSung, Jin Sol; Kang, Chan Woo; Kang, Suki, et alARTICLE84 ITGB4-mediated metabolic reprogramming of cancer-associated fibroblasts
2019-12MFF REGULATION OF MITOCHONDRIAL CELL DEATH IS A THERAPEUTIC TARGET IN CANCERSeo, Jae Ho; Chae, Young Chan; Kossenkov, Andrew V, et alARTICLE91 MFF REGULATION OF MITOCHONDRIAL CELL DEATH IS A THERAPEUTIC TARGET IN CANCER
2019-10Phospholipase C-β1 potentiates glucose-stimulated insulin secretionHwang, Hyeon-Jeong; Yang, Yong Ryoul; Kim, Hye Yun, et alARTICLE179 Phospholipase C-β1 potentiates glucose-stimulated insulin secretion
2019-10Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancerSeo, Jae Ho; Agarwal, Ekta; Chae, Young Chan, et alARTICLE80 Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer
2019-04Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cellsPark, Hye-Kyung; Hong, Jun-Hee; Oh, Young Taek, et alARTICLE180 Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells
2018-07Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial HypertensionBoucherat, Olivier; Peterlini, Thibaut; Bourgeois, Alice, et alARTICLE387 Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension
2018-07Cancer stem cell metabolism: target for cancer therapyChae, Young Chan; Kim, Jae HoARTICLE292 Cancer stem cell metabolism: target for cancer therapy
2018-03Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formationKim, Da Yeon; Jung, Seok Yun; Kim, Yeon Ju, et alARTICLE305 Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formation
2018-01PLCγ1: Potential arbitrator of cancer progressionJang, Hyun-Jun; Suh, Pann-Ghill; Lee, Yu Jin, et alARTICLE472 PLCγ1: Potential arbitrator of cancer progression
2017-12A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapyBryant, Kelly G.; Chae, Young Chan; Martinez, Rogelio L., et alARTICLE319 A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy
2016-08Mitochondrial Akt Regulation of Hypoxic Tumor ReprogrammingChae, Young Chan; Vaira, Valentina; Caino, M. Cecilia, et alARTICLE410 Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
2016-07The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and MetastasisSeo, Jae Ho; Rivadeneira, Dayana B.; Caino, M. Cecilia, et alARTICLE406 The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
2016-05Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitorsZhang, Gao; Frederick, Dennie T.; Wu, Lawrence, et alARTICLE435 Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors
2016-03Pairwise detection of site-specific receptor phosphorylations using single-molecule blottingKim, Kyung Lock; Kim, Daehyung; Lee, Seongsil, et alARTICLE434 Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
2015-07PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasionCaino, M. Cecilia; Ghosh, Jagadish C.; Chae, Young Chan, et alARTICLE393 PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
2015-03Adaptive Mitochondrial Reprogramming and Resistance to PI3K TherapyGhosh, Jagadish C.; Siegelin, Markus D.; Vaira, Valentina, et alARTICLE296 Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy
2014-08Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic NetworksLisanti, Sofia; Tavecchio, Michele; Chae, Young Chan, et alARTICLE322 Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks
2013-07Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cellsCaino, M. Cecilia; Chae, Young Chan; Vaira, Valentina, et alARTICLE364 Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells

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