사진

Chae, Young Chan (채영찬)

Department
School of Life Sciences(생명과학부)
Research Interests
Cancer Metabolism, Stress Response of Cancer, Mitochondria of Cancer, Molecular Mechanisms of Cancer Initiation, Progression and Therapy, Autophagy in Cell Survival and Cancer Progression, Mechanism of tumor therapeutic resistance
Lab
Website
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2019-04Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cellsPark, Hye-Kyung; Hong, Jun-Hee; Oh, Young Taek, et alARTICLE98 Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells
2018-07Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial HypertensionBoucherat, Olivier; Peterlini, Thibaut; Bourgeois, Alice, et alARTICLE292 Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension
2018-07Cancer stem cell metabolism: target for cancer therapyChae, Young Chan; Kim, Jae HoARTICLE200 Cancer stem cell metabolism: target for cancer therapy
2018-03Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formationKim, Da Yeon; Jung, Seok Yun; Kim, Yeon Ju, et alARTICLE222 Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formation
2018-01PLCγ1: Potential arbitrator of cancer progressionJang, Hyun-Jun; Suh, Pann-Ghill; Lee, Yu Jin, et alARTICLE384 PLCγ1: Potential arbitrator of cancer progression
2017-12A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapyBryant, Kelly G.; Chae, Young Chan; Martinez, Rogelio L., et alARTICLE241 A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy
2016-08Mitochondrial Akt Regulation of Hypoxic Tumor ReprogrammingChae, Young Chan; Vaira, Valentina; Caino, M. Cecilia, et alARTICLE336 Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
2016-07The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and MetastasisSeo, Jae Ho; Rivadeneira, Dayana B.; Caino, M. Cecilia, et alARTICLE340 The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
2016-05Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitorsZhang, Gao; Frederick, Dennie T.; Wu, Lawrence, et alARTICLE358 Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors
2016-03Pairwise detection of site-specific receptor phosphorylations using single-molecule blottingKim, Kyung Lock; Kim, Daehyung; Lee, Seongsil, et alARTICLE373 Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
2015-07PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasionCaino, M. Cecilia; Ghosh, Jagadish C.; Chae, Young Chan, et alARTICLE328 PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
2015-03Adaptive Mitochondrial Reprogramming and Resistance to PI3K TherapyGhosh, Jagadish C.; Siegelin, Markus D.; Vaira, Valentina, et alARTICLE226 Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy
2014-08Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic NetworksLisanti, Sofia; Tavecchio, Michele; Chae, Young Chan, et alARTICLE257 Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks
2013-07Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cellsCaino, M. Cecilia; Chae, Young Chan; Vaira, Valentina, et alARTICLE298 Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
2013-07Landscape of the mitochondrial Hsp90 metabolome in tumoursChae, Young Chan; Angelin, Alessia; Lisanti, Sofia, et alARTICLE283 Landscape of the mitochondrial Hsp90 metabolome in tumours
2012-09Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90sChae, Young Chan; Caino, M. Cecilia; Lisanti, Sofia, et alARTICLE246 Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s
2010-11Protein Kinase C delta-Mediated Phosphorylation of Phospholipase D Controls Integrin-Mediated Cell SpreadingChae, Young Chan; Kim, Kyung Lock; Ha, Sang Hoon, et alARTICLE654 Protein Kinase C delta-Mediated Phosphorylation of Phospholipase D Controls Integrin-Mediated Cell Spreading
2009-12Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activityChae, Young Chan; Lee, Sukmook; Heo, Kyun, et alARTICLE683 Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity
2008-11Hydrogen Peroxide-Induced VCAM-1 Expression in Pancreatic Islets and beta-Cells Through Extracellular Ca2+ InfluxLee, Sukmook; Ha, In Su; Kim, Jae Hyeon, et alARTICLE606 Hydrogen Peroxide-Induced VCAM-1 Expression in Pancreatic Islets and beta-Cells Through Extracellular Ca2+ Influx
2008-09Epidermal growth factor increases insulin secretion and lowers blood glucose in diabetic miceLee, H. Y.; Yea, K.; Kim, J., et alARTICLE501 Epidermal growth factor increases insulin secretion and lowers blood glucose in diabetic mice

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