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Kim, Yong Hwan (김용환)

Department
School of Energy and Chemical Engineering(에너지화학공학과)
Website
https://sites.google.com/site/enzproyh/home
Lab
Enzyme and Protein Engineering Lab. (효소단백질공학 연구실)
Research Keywords
C1 gas conversion, Lignin conversion, Cosmetics application, Enzyme and Protein Engineering
Research Interests
Enzyme, a kind of specialized protein is biocatalyst to accelerate the reaction in living Biosystems by reducing the required activation energy barrier. Without enzymes, any cellular Biosystems cannot sustain its life system anymore. The acceleration of reaction and specificity of enzymes seems almost miracle since reaction rate can be increased up to billion times higher. Nowadays enzymes can be applied for not only living Biosystems but also chemical industries. Very mild reaction conditions such as room temperature, aqueous phase is enough for the synthesis of many kinds of value-added compounds such as pharmaceuticals, cosmetic ingredients and even bulk chemicals by employing enzymes as biocatalysts. However, even though enzymes seem miracle-like, its stability and reaction characteristics may be not optimized to be utilized for the chemical process.Our lab is actively trying to engineer these enzymes to be more optimized and superior biocatalysts capable of converting raw material to value-added compounds through rational and 3D structure-based design of biocatalysts.
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2022-06Bioconversion of CO to formate by artificially designed carbon monoxide:formate oxidoreductase in hyperthermophilic archaeaLim, Jae Kyu; Yang, Ji-In; Kim, Yun Jae, et alARTICLE63 Bioconversion of CO to formate by artificially designed carbon monoxide:formate oxidoreductase in hyperthermophilic archaea
2022-04Microbial production of 2-pyrone-4,6-dicarboxylic acid from lignin derivatives in an engineered Pseudomonas putida and its application for the synthesis of bio-based polyesterLee, Siseon; Jung, Ye Jean; Park, Si Jae, et alARTICLE100 Microbial production of 2-pyrone-4,6-dicarboxylic acid from lignin derivatives in an engineered Pseudomonas putida and its application for the synthesis of bio-based polyester
2022-03Lignin as a multifunctional photocatalyst for solar-powered biocatalytic oxyfunctionalization of C–H bondsJinhyun Kim; Trang Vu Thien Nguyen; Kim, Yong Hwan, et alARTICLE53 Lignin as a multifunctional photocatalyst for solar-powered biocatalytic oxyfunctionalization of C–H bonds
2022-03Unbiased Photoelectrode Interfaces for Solar Coupling of Lignin Oxidation with Biocatalytic C=C Bond HydrogenationKim, Jinhyun; Um, Yunna; Han, Seunghyun, et alARTICLE12 Unbiased Photoelectrode Interfaces for Solar Coupling of Lignin Oxidation with Biocatalytic C=C Bond Hydrogenation
2022-01Effect of manganese peroxidase on the decomposition of cellulosic components: Direct cellulolytic activity and synergistic effect with cellulaseMin, Kyoungseon; Kim, Yong Hwan; Kim, Jiye, et alARTICLE123 Effect of manganese peroxidase on the decomposition of cellulosic components: Direct cellulolytic activity and synergistic effect with cellulase
2021-08Extra disulfide and ionic salt bridge improves the thermostability of lignin peroxidase H8 under acidic conditionSon, Haewon; Seo, Hogyun; Han, Seunghyun, et alARTICLE225 Extra disulfide and ionic salt bridge improves the thermostability of lignin peroxidase H8 under acidic condition
2020-08Lignin-fueled photoelectrochemical platform for light-driven redox biotransformationWang, Ding; Lee, Sahng Ha; Han, Seunghyun, et alARTICLE397 Lignin-fueled photoelectrochemical platform for light-driven redox biotransformation
2020-06Two-stage bioconversion of carbon monoxide to biopolymers via formate as an intermediateHwang, Ho Won; Yoon, Jihee; Min, Kyoungseon, et alARTICLE547 Two-stage bioconversion of carbon monoxide to biopolymers via formate as an intermediate
2020-05Robust FeOOH/BiVO4/Cu(In, Ga)Se2 tandem structure for solar-powered biocatalytic CO2 reductionKim, Jinhyun; Lee, Yang Woo; Choi, Eun-Gyu, et alARTICLE284 Robust FeOOH/BiVO4/Cu(In, Ga)Se2 tandem structure for solar-powered biocatalytic CO2 reduction
2020-02Phosphomolybdic Acid as a Catalyst for Oxidative Valorization of Biomass and Its Application as an Alternative Electron SourceOh, Hyeonmyeong; Choi, Yuri; Shin, Changhwan, et alARTICLE414 Phosphomolybdic Acid as a Catalyst for Oxidative Valorization of Biomass and Its Application as an Alternative Electron Source
2019-11Unassisted solar lignin valorisation using a compartmented photo-electro-biochemical cellKo, Myohwa; Pham, Le Thanh Mai; Sa, Young Jin, et alARTICLE556 Unassisted solar lignin valorisation using a compartmented photo-electro-biochemical cell
2019-09Recombinant lignin peroxidase-catalyzed decolorization of melanin using in-situ generated H2O2 for application in whitening cosmeticsSung, Ho Jun; Khan, Mohd Faheem; Kim, Yong HwanARTICLE449 Recombinant lignin peroxidase-catalyzed decolorization of melanin using in-situ generated H2O2 for application in whitening cosmetics
2019-09Adaptively evolved Escherichia coli for improved ability of formate utilization as a carbon source in sugar‑free conditionsKim, Seung‑Jin; Yoon, Jihee; Im, Dae‑Kyun, et alARTICLE500 Adaptively evolved Escherichia coli for improved ability of formate utilization as a carbon source in sugar‑free conditions
2019-02Enzymatic Synthesis of D-pipecolic Acid by Engineering the Substrate Specificity of Trypanosoma cruzi Proline Racemase and Its Molecular Docking StudyByun, Sungmin; Park, Hyun Jun; Joo, Jeong Chan, et alARTICLE433 Enzymatic Synthesis of D-pipecolic Acid by Engineering the Substrate Specificity of Trypanosoma cruzi Proline Racemase and Its Molecular Docking Study
2018-12In silico-designed lignin peroxidase from Phanerochaete chrysosporium shows enhanced acid stability for depolymerization of ligninPham, Le Thanh Mai; Seo, Hogyun; Kim, Kyung Jin, et alARTICLE623 In silico-designed lignin peroxidase from Phanerochaete chrysosporium shows enhanced acid stability for depolymerization of lignin
2018-09Electrochemical synthesis of formic acid from CO2 catalyzed by Shewanella oneidensis MR-1 whole-cell biocatalystLe, Quang Anh Tuan; Kim, Hee Gon; Kim, Yong HwanARTICLE821 Electrochemical synthesis of formic acid from CO2 catalyzed by Shewanella oneidensis MR-1 whole-cell biocatalyst
2018-09CO2 Reduction to Formate: An Electro-Enzymatic Approach Using a Formate Dehydrogenase from Rhodobacter capsulatusChoi, Eun-Gyu; Yeon, Young Joo; Min, Kyoungseon, et alARTICLE1031 CO2 Reduction to Formate: An Electro-Enzymatic Approach Using a Formate Dehydrogenase from Rhodobacter capsulatus
2018-09Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solventsKim, Hanyong; Yoo, Hah Young; Kim, Yong Hwan, et alARTICLE607 Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents
2018-09A Photoenzymatic NADH regeneration systemHçfler, Georg T.; Fernandes-Fueyo, Elena; Pesic, Milja, et alARTICLE641 A Photoenzymatic NADH regeneration system
2018-05Bioelectrochemical conversion of CO2 to value added product formate using engineered Methylobacterium extorquensJang, Jungho; Jeon, Byoung Wook; Kim, Yong HwanARTICLE1056 Bioelectrochemical conversion of CO2 to value added product formate using engineered Methylobacterium extorquens

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