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Lee, Semin (이세민)

Department
Department of Biomedical Engineering(바이오메디컬공학과)
Website
http://compbio.unist.ac.kr
Lab
Computational Biology Lab. (계산생물학 실험실)
Research Keywords
구조생명정보학, 기계학습, 정밀의학, 암유전체학, 단일세포오믹스, Cancer genomics, single-cell omics, structural bioinformatics, machine learning, precision medicine
Research Interests
We analyze a large number of cancer genomes using multiple omics approaches to characterize various kinds of germline/somatic alterations in many different human cancer types. In order to understand somatic mosaicism, heterogeneity, and evolution in cancer, we also use single-cell genomics approaches.
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2023-11Single-cell RNA Sequencing Reveals Novel Cellular Factors for Response to Immunosuppressive Therapy in Aplastic AnemiaJang, Jinho; Kim, Hongtae; Park, Sung-Soo, et alARTICLE27 Single-cell RNA Sequencing Reveals Novel Cellular Factors for Response to Immunosuppressive Therapy in Aplastic Anemia
2023-07Genomic characteristics of triple negative apocrine carcinoma: a comparison to triple negative breast cancerKim, Ji-Yeon; Park, Sabin; Cho, Eun Yoon, et alARTICLE731 Genomic characteristics of triple negative apocrine carcinoma: a comparison to triple negative breast cancer
2023-06Prediction of Treatment Response to Chemoimmunotherapy: Concerted Effort NeededLim, Jun Hyeok; Lee, Semin; Ryu, Jeong-SeonARTICLE440 Prediction of Treatment Response to Chemoimmunotherapy: Concerted Effort Needed
2023-06Experimental systems for the analysis of mutational signatures: no 'one-size-fits-all' solutionIvanov, Dmitri; Hwang, Taejoo; Sitko, Lukasz Karol, et alARTICLE729 Experimental systems for the analysis of mutational signatures: no 'one-size-fits-all' solution
2023-05A heterozygous mutation in UBE2H in a patient with developmental delay leads to an aberrant brain development in zebrafishShin, Unbeom; Choi, Yeonsong; Ko, Hwa Soo, et alARTICLE488 A heterozygous mutation in UBE2H in a patient with developmental delay leads to an aberrant brain development in zebrafish
2023-02GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasisLee, Yu Jin; Shin, Kyeong Jin; Jang, Hyun-Jun, et alARTICLE895 GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
2023-01RAMP: response-aware multi-task learning with contrastive regularization for cancer drug response predictionLee, Kanggeun; Cho, Dongbin; Jang, Jinho, et alARTICLE1409 RAMP: response-aware multi-task learning with contrastive regularization for cancer drug response prediction
2022-12Randomized multicenter phase II trial of prophylactic irradiation of para-aortic lymph nodes in advanced cervical cancer according to tumor hypoxia: Korean Radiation Oncology Group (KROG 07-01) studyYoon, Meesun; Lee, Hyo Kyung; Park, Eun Young, et alARTICLE953 Randomized multicenter phase II trial of prophylactic irradiation of para-aortic lymph nodes in advanced cervical cancer according to tumor hypoxia: Korean Radiation Oncology Group (KROG 07-01) study
2022-11Cellular plasticity and immune microenvironment of malignant pleural effusion are associated with EGFR-TKI resistance in non-small-cell lung carcinomaJeong, Hyoung-oh; Lee, Hayoon; Kim, Hyemin, et alARTICLE447 Cellular plasticity and immune microenvironment of malignant pleural effusion are associated with EGFR-TKI resistance in non-small-cell lung carcinoma
2022-07PWWP2B promotes DNA end resection and homologous recombinationJu, Min Kyung; Lee, Joo Rak; Choi, Yeonsong, et alARTICLE1153 PWWP2B promotes DNA end resection and homologous recombination
2022-04Somatic mosaicism reveals clonal distributions of neocortical developmentBreuss, Martin W.; Yang, Xiaoxu; Schlachetzki, Johannes C. M., et alARTICLE587 Somatic mosaicism reveals clonal distributions of neocortical development
2022-02A functional genomic approach to actionable gene fusions for precision oncologyLi, Jun; Lu, Hengyu; Ng, Patrick Kwok-Shing, et alARTICLE390 A functional genomic approach to actionable gene fusions for precision oncology
2022-01Comparison of 3-month cytogenetic and molecular assays for early assessment of long-term clinical impact after BCR-ABL1 tyrosine kinase inhibitor treatment in chronic myeloid leukemiaKee, Kyung-Mi; Kim, Soo-Hyun; Yang, Seon-Young, et alARTICLE626 Comparison of 3-month cytogenetic and molecular assays for early assessment of long-term clinical impact after BCR-ABL1 tyrosine kinase inhibitor treatment in chronic myeloid leukemia
2022-01Sex-specific difference of in-hospital mortality from COVID-19 in South KoreaHer, Ae-Young; Bhak, Youngjune; Jun, Eun Jung, et alARTICLE521 Sex-specific difference of in-hospital mortality from COVID-19 in South Korea
2021-11Circulating Tumor Cell Clusters Are Cloaked with Platelets and Correlate with Poor Prognosis in Unresectable Pancreatic CancerLim, Minji; Park, Suhyun; Jeong, Hyoung-Oh, et alARTICLE580 Circulating Tumor Cell Clusters Are Cloaked with Platelets and Correlate with Poor Prognosis in Unresectable Pancreatic Cancer
2021-10Loss of BubR1 acetylation provokes replication stress and leads to complex chromosomal rearrangementsPark, Jiho; Yeu, Song Y.; Paik, Sangjin, et alARTICLE641 Loss of BubR1 acetylation provokes replication stress and leads to complex chromosomal rearrangements
2021-08Microbiome of Saliva and Plaque in Children According to Age and Dental Caries ExperienceLee, Eungyung; Park, Suhyun; Um, Sunwoo, et alARTICLE604 Microbiome of Saliva and Plaque in Children According to Age and Dental Caries Experience
2021-07Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancerKim, Miok; Min, Yong Ki; Jang, Jinho, et alARTICLE945 Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer
2021-04An integrated mRNA-microRNA regulatory network identified INHBA and has-miR-135a-5p as predictors of gastric cancer recurrenceSohn, Sung-Hwa; Sul, Hee Jung; Choi, Yeonsong, et alARTICLE676 An integrated mRNA-microRNA regulatory network identified INHBA and has-miR-135a-5p as predictors of gastric cancer recurrence
2021-04A Clinical Risk Score to Predict In-hospital Mortality from COVID-19 in South KoreaHer, Ae-Young; Bhak, Youngjune; Jun, Eun Jung, et alARTICLE699 A Clinical Risk Score to Predict In-hospital Mortality from COVID-19 in South Korea

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