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Lee, Changwook (이창욱)

Department
School of Life Sciences(생명과학부)
Research Interests
Cell biology, structural biology, protein biochemistry, membrane biology, cancer biology
Lab
Structural Biology of Cellular Biochemistry Lab
Website
https://sites.google.com/site/changwooklab/
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2020-01Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1Jung, Sejin; Yoon, Nam Gu; Yang, Sujae, et alARTICLE14 Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1
2019-09Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways.Park, Jumi; Kim, Hye-In; Jeong, Hanbin, et alARTICLE144 Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways.
2019-07The structure of human EXD2 reveals a chimeric 3′ to 5′ exonuclease domain that discriminates substrates via metal coordinationPark, Jumi; Lee, Song-Yi; Jeong, Hanbin, et alARTICLE201 The structure of human EXD2 reveals a chimeric 3′ to 5′ exonuclease domain that discriminates substrates via metal coordination
2019-03Ergosterol interacts with Sey1p to promote atlastin-mediated endoplasmic reticulum membrane fusion in Saccharomyces cerevisiaeLee, Miriam; Moon, Yeojin; Lee, Sanghwa, et alARTICLE165 Ergosterol interacts with Sey1p to promote atlastin-mediated endoplasmic reticulum membrane fusion in Saccharomyces cerevisiae
2018-12Identification of a novel GPR143 mutation in X-linked ocular albinism with marked intrafamilial phenotypic variabilityJung, Jae-Ho; Oh, Eun Hye; Shin, Jin-Hong, et alARTICLE173 Identification of a novel GPR143 mutation in X-linked ocular albinism with marked intrafamilial phenotypic variability
2018-06Genotype and Phenotype Spectrum of FRMD7-Associated Infantile Nystagmus SyndromeChoi, Jae-Hwan; Jung, Jae-Ho; Oh, Eun Hye, et alARTICLE222 Genotype and Phenotype Spectrum of FRMD7-Associated Infantile Nystagmus Syndrome
2017-11Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sitesJeong, Hanbin; Park, Jumi; Jun, Youngsoo, et alARTICLE420 Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites
2017-09Rogdi Defines GABAergic Control of a Wake-promoting Dopaminergic Pathway to Sustain Sleep in DrosophilaKim, Minjong; Jang, Donghoon; Yoo, Eunseok, et alARTICLE442 Rogdi Defines GABAergic Control of a Wake-promoting Dopaminergic Pathway to Sustain Sleep in Drosophila
2017-09Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 InhibitorsPark, Hye-Kyung; Jeong, Hanbin; Ko, Eunhwa, et alARTICLE455 Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors
2017-09Purification, crystallization, and X-ray crystallographic analysis of Vac8p complexed with Atg13p from Saccharomyces cerevisiaePark, Jumi; Song, Kyonghwa; Oh, Sohyeon, et alARTICLE219
2017-08Molecular mechanisms of atlastin-mediated ER membrane fusion revealed by a FRET-based single-vesicle fusion assayKim, Kyung Tae; Moon, Yeojin; Jang, Yunsu, et alARTICLE361 Molecular mechanisms of atlastin-mediated ER membrane fusion revealed by a FRET-based single-vesicle fusion assay
2017-08Structure-guided synthesis of a protein-based fluorescent sensor for alkyl halidesKang, Myeong-Gyun; Lee, Hakbong; Kim, Beom Ho, et alARTICLE474 Structure-guided synthesis of a protein-based fluorescent sensor for alkyl halides
2017-06The crystal structure of human Rogdi provides insight into the causes of Kohlschutter-Tonz SyndromeLee, Hakbong; Jeong, Hanbin; Choe, Joonho, et alARTICLE443 The crystal structure of human Rogdi provides insight into the causes of Kohlschutter-Tonz Syndrome
2017-06Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structureJeong, Hanbin; Park, Jumi; Kim, Hye-In, et alARTICLE492 Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure
2017-04Genetically Encodable Bacterial Flavin Transferase for Fluorogenic Protein Modification in Mammalian CellsKang, Myeong-Gyun; Park, Jumi; Balboni, Gianfranco, et alARTICLE470 Genetically Encodable Bacterial Flavin Transferase for Fluorogenic Protein Modification in Mammalian Cells
2016-12Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complexJeong, Hanbin; Park, Jumi; Lee, ChangwookARTICLE763 Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex
2016-08Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live CellsLee, Song-Yi; Lee, Hakbong; Lee, Hye-Kyeong, et alARTICLE663 Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live Cells
2016-04LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA bindingLee, Hwan Hee; Sanada, Satoru; An, Seung Min, et alARTICLE712 LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding
2016-02Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathwayJeong, Hanbin; Sim, Hyo Jung; Song, Eun Kyung, et alARTICLE718 Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway
2015-04Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1Lee, Changwook; Park, Hye-Kyung; Jeong, Hanbin, et alARTICLE829 Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1

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