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유자형
Ryu, Ja-Hyoung

유자형

Department of Chemistry(화학과)

  • Supramolecular Nanomaterials Lab.
  • Website
Research Interests
Supramolecular assembly;Self-assembled structures;Drug Delivery System;Cancer Therapy;초분자 자기조립;자기조립 구조;항암 치료;약물전달 시스템
Lab Description
Our research focus on establishing self-transformable nano-architectures by external stimuli for new nano-, bio-materials through elaborate molecular design and chemical synthetic tools. The assembly and transformation of biomacromolecules in response to a signal (or a stimulus) is an important component to most of Nature’s functions and signaling mechanisms. Given the versatile nature of such stimuli-responsive assembly and disassembly processes, it is desirable to understand and develop ways by which artificial, responsive supramolecular assemblies could be achieved. Development of artificial assemblies with nature’s specificity and versatility stands as an enormous intellectual challenge and custom-designed stimuli-sensitive supramolecular assemblies have potential in a variety of applications.
Researcher ID Research Gate ORCiD Scopus Google Scholar
Previous
Drug-Loaded Nanogel for Efficient Orchestration of Cell Death Pathways by Intramitochondrial Disulfide Polymerization File

Choi, Eun Seong , Kim, Sangpil , Kim, Dohyun , Choi, Eunshil , Ryu, Ja-Hyoung

Article Issue Date2023-11 View7
Azacyclic Anchor-Enabled Cohesive Graphite Electrodes for Sustainable Anion Storage File

Kang, Jieun , Lee, Seungho , Hwang, Jinwoo , Kim, Sungho , Lee, Sangyeop , Yoo, Seokkeun , Han, Jeong Woo , Ryu, Ja-Hyoung , Ryu, Jaegeon , Park, Soojin

Article Issue Date2023-11 View6
Surface protein-retractive and redox-degradable mesoporous organosilica nanoparticles for enhanced cancer therapy File

Yang, Gyeongseok , Kim, Sangpil , Oh, Jun Yong , Kim, Dohyun , Jin, Seongeon , Choi, Eunshil , Ryu, Ja-Hyoung

Article Issue Date2023-11 View24
Metal–Organic Framework-Supported Catalase Delivery for Enhanced Photodynamic Therapy via Hypoxia Mitigation File

Sim, Youjung , Seong, Junmo , Lee, Seonghwan , Kim, Dohyun , Choi, Eunshil , Lah, Myoung Soo , Ryu, Ja-Hyoung

Article Issue Date2023-11 View10
Supramolecular Senolytics via Intracellular Oligomerization of Peptides in Response to Elevated Reactive Oxygen Species Levels in Aging Cells File

Kim, Sangpil , Chae, Jae-Byoung , Kim, Dohyun , Park, Chul-Woo , Sim, Youjung , Lee, Hyungwoo , Park, Gaeun , Lee, Jaeeun , Hong, Seongho , Jana, Batakrishna , et al

Article Issue Date2023-10 View30
Intra-Lysosomal Peptide Assembly for the High Selectivity Index against Cancer File

Jana, Batakrishna , Jin, Seongeon , Go, Eun Min , Cho, Yumi , Kim, Dohyun , Kim, Sangpil , Kwak, Sang Kyu , Ryu, Ja-Hyoung

Article Issue Date2023-08 View5
Antibody plug-and-playable nanoparticles as a facile and versatile platform for targeted drug delivery File

Oh, Jun Yong , An, Eun-Koung , Jana, Batakrishna , Kim, Hansol , Jin, Seongeon , Yang, Gyeongseok , Kim, Jinsoo , Choi, Eunshil , Jin, Jun-O , Ryu, Ja-Hyoung

Article Issue Date2023-08 View11
Protein-Precoated Surface of Metal-Organic Framework Nanoparticles for Targeted Delivery File

Oh, Jun Yong , Choi, Eunshil , Jana, Batakrishna , Go, Eun Min , Jin, Eunji , Jin, Seongeon , Lee, Jinhyu , Bae, Jong-hoon , Yang, Gyeongseok , Kwak, Sang Kyu , et al

Article Issue Date2023-06 View13
Self-assembly inside cellular organelles: Aspects of functions and various strategies for cancer therapy File File

Kim, Sangpil , Choi, Huyeon , Jin, Seongeon , Son, Sehee , Lee, Yeji , Kim, Kibeom , Ryu, Ja-Hyoung

Article Issue Date2023-02 View10
Cancer-Selective Supramolecular Chemotherapy by Disassembly-Assembly Approach File

Jeena, M.T. , Jin, Sungeon , Jeong, Keunsoo , Cho, Yuri , Kim, Jin Chul , Lee, Jeong Hyeon , Lee, Seokyoung , Hwang, Suk-Won , Kwak, Sang Kyu , Kim, Sehoon , et al

Article Issue Date2022-12 View32
Enzyme-instructed morphology transformation of mitochondria-targeting peptide for the selective eradication of osteosarcoma File

Jeena, M.T. , Jin, Seongeon , Jana, Batakrishna , Ryu, Ja-Hyoung

Article Issue Date2022-12 View12
Spatiotemporal Self-Assembly of Peptide Amphiphiles by Carbonic Anhydrase IX-Targeting Induces Cancer-Lysosomal Membrane Disruption File

Kim, Dohyun , Kim, Sangpil , Park, Gaeun , Choi, Huyeon , Ryu, Ja-Hyoung

Article Issue Date2022-11 View10
Ion slippage through Li+-centered G-quadruplex File File

Cho, Seok-Kyu , Lee, Kyung Min , Kang, So-Huei , Jeong, Kihun , Han, Sun-Phil , Lee, Ji Eun , Lee, Seungho , Shin, Tae Joo , Ryu, Ja-Hyoung , Yang, Changduk , et al

Article Issue Date2022-09 View11
Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin File File

Lee, Hyungwoo , Lee, Ho-Yeon , Chae, Jae-Byoung , Park, Chul-Woo , Kim, Chaekyu , Ryu, Ja-Hyoung , Jang, Jiwon , Kim, Namshin , Chung, Hyewon

Article Issue Date2022-07 View7
Comparison of the immune activation capacities of fucoidan and laminarin extracted from Laminaria japonica File

An, Eun-Koung , Hwang, Juyoung , Kim, So-Jung , Park, Hae-Bin , Zhang, Wei , Ryu, Ja-Hyoung , You, SangGuan , Jin, Jun-O

Article Issue Date2022-05 View17
Intramitochondrial co-assembly between ATP and nucleopeptides induces cancer cell apoptosis File File

Choi, Huyeon , Park, Gaeun , Shin, Eunhye , Shin, Seon Woo , Jana, Batakrishna , Jin, Seongeon , Kim, Sangpil , Wang, Huaimin , Kwak, Sang Kyu , Xu, Bing , et al

Article Issue Date2022-04 View10
Stimuli-Responsive Adaptive Nanotoxin to Directly Penetrate the Cellular Membrane by Molecular Folding and Unfolding File

Jeong, Youngdo , Jin, Soyeong , Palanikumar, L. , Choi, Huyeon , Shin, Eunhye , Go, Eun Min , Keum, Changjoon , Bang, Seunghwan , Kim, Dongkap , Lee, Seungho , et al

Article Issue Date2022-03 View18
Quaternary ammonium-based mitochondria targeting anticancer agents with high water solubility File

Kim, Sangpil , Yoon, Nam Gu , Jana, Batakrishna , Kang, Byoung Heon , Ryu, Ja-Hyoung

Article Issue Date2022-03 View5
Creating Tunable Mesoporosity by Temperature‐Driven Localized Crystallite Agglomeration File

Jeong, Seok , Sim, Youjung , Kim, Jin Kyun , Shin, Sunyoung , Lim, Jaewoong , Seong, Junmo , Lee, Seonghwan , Moon, Dohyun , Baek, Seung Bin , Kim, Chae Un , et al

Article Issue Date2022-02 View5
Mesoporous silica nanoparticle-supported nanocarriers with enhanced drug loading, encapsulation stability, and targeting efficiency File

Oh, Jun Yong , Yang, Gyeongseok , Choi, Eunshil , Ryu, Ja-Hyoung

Article Issue Date2022-02 View9
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