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Ryu, Ja-Hyoung (유자형)

Department
Department of Chemistry(화학과)
Website
http://jhryu.unist.ac.kr
Lab
Supramolecular Nanomaterials Lab. (초분자재료화학 연구실)
Research Keywords
초분자 자기조립, 자기조립 구조, 항암 치료, 약물전달 시스템, Supramolecular assembly, Self-assembled structures, Drug Delivery System, Cancer Therapy
Research Interests
Our research focus on establishing self-transformable nano-architectures by external stimuli for new nano-, bio-materials through elaborate molecular design and chemical synthetic tools. The assembly and transformation of biomacromolecules in response to a signal (or a stimulus) is an important component to most of Nature’s functions and signaling mechanisms. Given the versatile nature of such stimuli-responsive assembly and disassembly processes, it is desirable to understand and develop ways by which artificial, responsive supramolecular assemblies could be achieved. Development of artificial assemblies with nature’s specificity and versatility stands as an enormous intellectual challenge and custom-designed stimuli-sensitive supramolecular assemblies have potential in a variety of applications.
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2022-04Intramitochondrial co-assembly between ATP and nucleopeptides induces cancer cell apoptosisChoi, Huyeon; Park, Gaeun; Shin, Eunhye, et alARTICLE21 Intramitochondrial co-assembly between ATP and nucleopeptides induces cancer cell apoptosis
2022-02Creating Tunable Mesoporosity by Temperature‐Driven Localized Crystallite AgglomerationJeong, Seok; Sim, Youjung; Kim, Jin Kyun, et alARTICLE87 Creating Tunable Mesoporosity by Temperature‐Driven Localized Crystallite Agglomeration
2022-02Mesoporous silica nanoparticle-supported nanocarriers with enhanced drug loading, encapsulation stability, and targeting efficiencyOh, Jun Yong; Yang, Gyeongseok; Choi, Eunshil, et alARTICLE67 Mesoporous silica nanoparticle-supported nanocarriers with enhanced drug loading, encapsulation stability, and targeting efficiency
2021-12Targeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degenerationChae, Jae-Byoung; Jang, Hyoik; Son, Chanok, et alARTICLE128 Targeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degeneration
2021-12Mitochondrial Membrane Disrupting Molecules for Selective Killing of Senescent CellsJana, Batakrishna; Kim, Sangpil; Chae, Jae-Byoung, et alARTICLE68 Mitochondrial Membrane Disrupting Molecules for Selective Killing of Senescent Cells
2021-09Intramitochondrial Disulfide Polymerization Controls Cancer Cell FateKim, Sangpil; Jana, Batakrishna; Go, Eun Min, et alARTICLE95 Intramitochondrial Disulfide Polymerization Controls Cancer Cell Fate
2021-04Drug resistance-free cytotoxic nanodrugs in composites for cancer therapyJana, Batakrishna; Kim, Dongkap; Choi, Huyeon, et alARTICLE103 Drug resistance-free cytotoxic nanodrugs in composites for cancer therapy
2021-01Application of self-assembly peptides targeting the mitochondria as a novel treatment for sorafenib-resistant hepatocellular carcinoma cellsHong, Tae Ho; Jeena, M. T.; Kim, Ok-Hee, et alARTICLE160 Application of self-assembly peptides targeting the mitochondria as a novel treatment for sorafenib-resistant hepatocellular carcinoma cells
2020-12Intra-mitochondrial reaction for cancer cell imaging and anti-cancer therapy by aggregation-induced emissionKim, Sangpil; Kim, Juhee; Jana, Batakrishna, et alARTICLE208 Intra-mitochondrial reaction for cancer cell imaging and anti-cancer therapy by aggregation-induced emission
2020-12Spatiotemporal Self-Assembly of Peptides Dictates Cancer-Selective ToxicityJin, Seongeon; Jeena, M. T.; Jana, Batakrishna, et alARTICLE132 Spatiotemporal Self-Assembly of Peptides Dictates Cancer-Selective Toxicity
2020-09Novel Therapeutic Application of Self-Assembly Peptides Targeting the Mitochondria in In Vitro and In Vivo Experimental Models of Gastric CancerKim, Dong Jin; Jeena, M. T.; Kim, Ok-Hee, et alARTICLE145 Novel Therapeutic Application of Self-Assembly Peptides Targeting the Mitochondria in In Vitro and In Vivo Experimental Models of Gastric Cancer
2020-08Self‐Assembly of Mitochondria‐Targeted Photosensitizer to Increase Photostability and Photodynamic Therapeutic Efficacy in HypoxiaJana, Batakrishna; Thomas, Ajesh P.; Kim, Sangpil, et alARTICLE210 Self‐Assembly of Mitochondria‐Targeted Photosensitizer to Increase Photostability and Photodynamic Therapeutic Efficacy in Hypoxia
2020-06Intra-mitochondrial self-assembly to overcome the intracellular enzymatic degradation ofl-peptidesJeena, M. T.; Lee, Seokyoung; Barui, Ayan Kumar, et alARTICLE182 Intra-mitochondrial self-assembly to overcome the intracellular enzymatic degradation ofl-peptides
2020-03Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting DrugHu, Sung; Ferraro, Mariarosaria; Thomas, Ajesh P., et alARTICLE239 Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting Drug
2020-02Room‐Temperature Crosslinkable Natural Polymer Binder for High‐Rate and Stable Silicon AnodesRyu, Jaegeon; Kim, Sungho; Kim, Jimin, et alARTICLE388 Room‐Temperature Crosslinkable Natural Polymer Binder for High‐Rate and Stable Silicon Anodes
2020-01Supramolecular protection-mediated one-pot synthesis of cationic gold nanoparticlesJana, Batakrishna; Kim, Seongchan; Choi, Huyeon, et alARTICLE481 Supramolecular protection-mediated one-pot synthesis of cationic gold nanoparticles
2020-01Cancer-targeted nanomedicine: overcoming the barrier of protein coronaBarui, Ayan Kumar; Oh, Jun Yong; Jana, Batakrishna, et alARTICLE349 Cancer-targeted nanomedicine: overcoming the barrier of protein corona
2020-01Recent progress in mitochondria-targeted drug and drug-free agents for cancer therapyJeena, M.T.; Kim, Sangpil; Jin, Seongeon, et alARTICLE389 Recent progress in mitochondria-targeted drug and drug-free agents for cancer therapy
2019-10Mitochondrial Heat Shock Protein-Guided Photodynamic TherapyThomas, Ajesh P.; Lee, An-Jung; Palanikumar, L, et alARTICLE396 Mitochondrial Heat Shock Protein-Guided Photodynamic Therapy
2019-09Heterochiral Assembly of Amphiphilic Peptides Inside the Mitochondria for Supramolecular Cancer TherapeuticsJeena, M. T.; Jeong, Keunsoo; Go, Eun Min, et alARTICLE458 Heterochiral Assembly of Amphiphilic Peptides Inside the Mitochondria for Supramolecular Cancer Therapeutics

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