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Kim, Jeong Beom (김정범)

Department
Department of Biomedical Engineering(바이오메디컬공학과)
Website
http://jbkim.unist.ac.kr/
Lab
Molecular Biomedicine Lab. (분자생의학 연구실)
Research Keywords
분자생의학, 줄기세포, 3D 바이오 프린팅, 오가노이드, Reprogramming, Direct conversion, 3D bioprinting, Spinal cord injury, Neurodegenerative diseases, Molecular Biomedicine
Research Interests
Molecular Biomedicine Lab (MBL) is a global stem cell research group that has a network with Max Planck Institute, the world-leading research institute. MBL aims to develop novel stem cell technologies to treat incurable disease. Direct conversion is a technology that can generate target cells from skin cells by bypassing the pluripotent stage thereby solving the tumorigenic risk of pluripotent stem cells. MBL focuses on developing stem cell treatments that repair damaged tissues or damaged organs using patient-specific stem cells generated by direct conversion technology, organoid technology or stem cellbased tissues produced by 3D bio-printing technology.Our research is based on an understanding of the mechanism of iPS reprogramming, direct conversion and the generation of patientspecific stem cells for future cell therapy. The aim is to develop innovative cell therapeutic methods for clinical applications and possible solutions for degenerative and currently incurable disease. In addition, iPS cells and direct conversion can also be used for innovative techniques of drug screening and toxicity tests. Therefore, the therapeutic potential of iPS cell and direct converted cells are very promising.
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2021-03Synergistic control of mechanics and microarchitecture of 3D bioactive hydrogel platform to promote the regenerative potential of engineered hepatic tissueKim, Suntae; Park, Myung Rae; Choi, Cholong, et alARTICLE18 Synergistic control of mechanics and microarchitecture of 3D bioactive hydrogel platform to promote the regenerative potential of engineered hepatic tissue
2020-06Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury modelLee, Hyunah; Lee, Hye Yeong; Lee, Byeong Eun, et alARTICLE180 Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model
2020-05SPON1 Can Reduce Amyloid Beta and Reverse Cognitive Impairment and Memory Dysfunction in Alzheimer's Disease Mouse ModelPark, Soo Yong; Kang, Joo Yeong; Lee, Taehee, et alARTICLE36 SPON1 Can Reduce Amyloid Beta and Reverse Cognitive Impairment and Memory Dysfunction in Alzheimer's Disease Mouse Model
2020-04Decellularized extracellular matrix-based bio-ink with enhanced 3D printability and mechanical propertiesKim, Min Kyeong; Jeong, Wonwoo; Lee, Sang Min, et alARTICLE1347 Decellularized extracellular matrix-based bio-ink with enhanced 3D printability and mechanical properties
2020-04Etv2- and Fli1-Induced Vascular Progenitor Cells Enhance Functional Recovery in Ischemic Vascular Disease Model-Brief ReportPark, Soo Yong; Lee, Hyunah; Kwon, Yang Woo, et alARTICLE95 Etv2- and Fli1-Induced Vascular Progenitor Cells Enhance Functional Recovery in Ischemic Vascular Disease Model-Brief Report
2020-02Direct monitoring of live human pluripotent stem cells by a highly selective pluripotency sensorPark, Myung Rae; Nam, Donggyu; Lee, Hyunah, et alARTICLE103 Direct monitoring of live human pluripotent stem cells by a highly selective pluripotency sensor
2019-08Oct4 and Hnf4 alpha-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis modelPark, Myung Rae; Wong, Man Sze; Arauzo-Bravo, Marcos J., et alARTICLE200 Oct4 and Hnf4 alpha-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model
2019-07Flexibility Enhancement of Poly(lactide-co-glycolide) for Fused Deposition Modeling TechnologyJeon, Seunggyu; Han, Jonghyeuk; Jeong, Wonwoo, et alARTICLE549 Flexibility Enhancement of Poly(lactide-co-glycolide) for Fused Deposition Modeling Technology
2017-11Regulation of cAMP and GSK3 signaling pathways contributes to the neuronal conversion of gliomaOh, Jinsoo; Kim, Yongbo; Che, Lihua, et alARTICLE599 Regulation of cAMP and GSK3 signaling pathways contributes to the neuronal conversion of glioma
2016-03Induced neural stem cells from distinct genetic backgrounds exhibit different reprogramming statusKim, Sung Min; Lim, Kyung Tae; Kwak, Tae Hwan, et alARTICLE864 Induced neural stem cells from distinct genetic backgrounds exhibit different reprogramming status
2016-02Establishment of feeder-free culture system for human induced pluripotent stem cell on DAS nanocrystalline grapheneLee, Hyunah; Nam, Donggyu; Choi, Jae Kyung, et alARTICLE1252 Establishment of feeder-free culture system for human induced pluripotent stem cell on DAS nanocrystalline graphene
2016-02Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming FactorsHermann, Andreas; Kim, Jeong Beom; Srimasorn, Sumitra, et alARTICLE872 Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors
2015-12Oct4-induced oligodendrocyte progenitor cells enhance functional recovery in spinal cord injury modelKim, Jeong Beom; Lee, Hyunah; Arauzo-Bravo, Marcos J, et alARTICLE740 Oct4-induced oligodendrocyte progenitor cells enhance functional recovery in spinal cord injury model
2015-07Controllable Synthesis of Graphene Encapsulated Low-Dimensional NanocompositesKim, Se-Yang; Kwak, Jinsung; Chu, Jae Hwan, et alARTICLE1162 Controllable Synthesis of Graphene Encapsulated Low-Dimensional Nanocomposites
2015-01Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of originKim, Jeong Beom; Dorn, Isabel; Klich, Katharina, et alARTICLE1386 Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin
2014-09Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brainHargus, Gunnar; Ehrlich, Marc; Arauzo-Bravo, Marcos J., et alARTICLE885 Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain
2012-10Polydopamine-mediated surface modification of scaffold materials for human neural stem cell engineeringYang, Kisuk; Lee, Jung Seung; Kim, Jin, et alARTICLE956 Polydopamine-mediated surface modification of scaffold materials for human neural stem cell engineering
2012-03Differentiation Efficiency of Induced Pluripotent Stem Cells Depends on the Number of Reprogramming FactorsLoehle, Matthias; Hermann, Andreas; Glass, Hannes, et alARTICLE863 Differentiation Efficiency of Induced Pluripotent Stem Cells Depends on the Number of Reprogramming Factors
2011-06Effects of neural progenitor cells on sensorimotor recovery and endogenous repair mechanisms after photothrombotic strokeMinnerup, Jens; Kim, Jeong Beom; Schmidt, Antje, et alARTICLE777 Effects of neural progenitor cells on sensorimotor recovery and endogenous repair mechanisms after photothrombotic stroke
2010-09Conversion of Mouse Epiblast Stem Cells to an Earlier Pluripotency State by Small MoleculesZhou, Hongyan; Li, Wenlin; Zhu, Saiyong, et alARTICLE764 Conversion of Mouse Epiblast Stem Cells to an Earlier Pluripotency State by Small Molecules

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